1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylic acid

Base Information

Chemical Name:1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylic acid
CAS No.:406476-31-1
Molecular Formula:C12H13 F3 N2 O2
Molecular Weight:274.243
Hs Code.:2933990090
European Community (EC) Number:692-235-6
DSSTox Substance ID:DTXSID40380656
Mol file:406476-31-1.mol

Synonyms:406476-31-1;1-(5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylic acid;1-[5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid;1-[5-(trifluoromethyl)-2-pyridyl]piperidine-4-carboxylic acid;5'-Trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-carboxylic acid;1-(5-(trifluoromethyl)-2-pyridyl)piperidine-4-carboxylic acid;Peakdale1_002677;SCHEMBL327492;HMS525J15;DTXSID40380656;MFCD00209248;(R)-(+)-1,2-BUTANEDIOL;AKOS000121943;AS-5488;CCG-238404;SB43304;SDCCGMLS-0066142.P001;CS-0072348;FT-0677793;EN300-00029;VU0494440-1;F50471;J-504124;Z56800753;F1686-0019;1-(5-Trifluoromethylpyrid-2-yl)-piperidine-4-carboxylic acid;1-[5-(trifluoromethyl)-2-pyridyl]-4-piperidinecarboxylic acid;1-[5-(trifluoromethyl)pyrid-2-yl]piperidine-4-carboxylic acid;4-Piperidinecarboxylicacid,1-[5-(trifluoromethyl)-2-pyridinyl]-;n-[5'-(trifluoromethyl)pyridin-2'-yl]piperidine-4-carboxylic acid;1-[5-(Trifluoromethyl)-2-pyridinyl]-4-piperidinecarboxylic acid, AldrichCPR

Suppliers and Price of 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
1-[5-(Trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid 97%
1 g
$ 56.00

SynQuest Laboratories
1-[5-(Trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid 97%
250 mg
$ 20.00

Matrix Scientific
5'-Trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-carboxylic acid
500mg
$ 182.00

Crysdot
1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylicacid 97%
10g
$ 297.00

Crysdot
1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylicacid 97%
25g
$ 594.00

CHESS?
PF100140:1-[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]PIPERIDINE-4-CARBOXYLICACID 97
5 g
$ 420.00

Chemenu
5''-Trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2'']bipyridinyl-4-carboxylicacid 97%
25g
$ 561.00

Chemenu
5''-Trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2'']bipyridinyl-4-carboxylicacid 97%
10g
$ 281.00

Chemenu
5''-Trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2'']bipyridinyl-4-carboxylicacid 97%
5g
$ 179.00

Atlantic Research Chemicals
1-[5-(Trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylicacid 95%
1gm:
$ 127.24

Total 24 raw suppliers

Chemical Property of 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylic acid

Chemical Property:

Appearance/Colour:off-white solid.
Vapor Pressure:8.29E-08mmHg at 25°C
Melting Point:162 ºC
Boiling Point:420.1 °C at 760 mmHg
Flash Point:207.9 °C
PSA：53.43000
Density:1.366 g/cm³
LogP:2.46640
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:274.09291215
Heavy Atom Count:19
Complexity:327

Purity/Quality:

97% ^*data from raw suppliers

1-[5-(Trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1C(=O)O)C2=NC=C(C=C2)C(F)(F)F

Technology Process of 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylic acid

There total 2 articles about 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 420844-59-3
ethyl 1-[5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylate

: 406476-31-1
1-(5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylic acid

Guidance literature:: ethyl 1-[5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylate; With potassium hydroxide; water; In methanol; at 40 ℃; for 0.5h;

With hydrogenchloride; pH=3;