2-Dibenzofuranmethanol

Base Information

• Chemical Name: 2-Dibenzofuranmethanol
• CAS No.: 86607-82-1
• Molecular Formula: C₁₃H₁₀O₂
• Molecular Weight: 198.221
• NSC Number: 155261
• DSSTox Substance ID: DTXSID701006951
• Wikidata: Q83002804
• Mol file: 86607-82-1.mol

Synonyms:2-Dibenzofuranmethanol;86607-82-1;dibenzofuran-2-ylmethanol;dibenzo[b,d]furan-2-ylmethanol;NSC155261;SCHEMBL2966131;DTXSID701006951;MFCD18451180;AKOS009333350;AT32579;NSC-155261;FT-0736030;{8-oxatricyclo[7.4.0.0(2),?]trideca-1(13),2(7),3,5,9,11-hexaen-4-yl}methanol;{8-oxatricyclo[7.4.0.0?,?]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl}methanol

Chemical Property of 2-Dibenzofuranmethanol

Chemical Property:

• Vapor Pressure: 2E-06mmHg at 25°C
• Boiling Point: 379.2°C at 760 mmHg
• Flash Point: 183.1°C
• Density: 1.284g/cm³
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 198.068079557
• Heavy Atom Count: 15
• Complexity: 229

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=C(O2)C=CC(=C3)CO

Technology Process of 2-Dibenzofuranmethanol

There total 11 articles about 2-Dibenzofuranmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

dibenzofuran-2-carbaldehyde (5397-82-0) → 2-hydroxymethyl-dibenzo[b,d]furan (86607-82-1)

Guidance literature:

dibenzofuran-2-carbaldehyde; With sodium tetrahydroborate; In tetrahydrofuran; at 20 ℃; for 2h;

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; for 0.333333h;

Reference yield: 94.0%

benzo[b,d]furan-2-carboxylic acid methyl ester (58841-72-8) → 2-hydroxymethyl-dibenzo[b,d]furan (86607-82-1)

Guidance literature:

With diisobutylaluminium hydride; In toluene; at -78 - 20 ℃; for 5h; Inert atmosphere;

DOI:10.1021/ol3023209

Reference yield: 56.0%

2-Bromo-4'-hydroxymethyldiphenyl ether (86607-78-5) → 2-hydroxymethyl-dibenzo[b,d]furan (86607-82-1)

Guidance literature:

With sodium carbonate; palladium diacetate; In N,N-dimethyl acetamide; at 170 ℃; for 24h;

DOI:10.1055/s-1983-30296

upstream raw materials:

dibenzofuran-2-carboxylic acid-(N-methyl-anilide)

2-Bromo-4'-hydroxymethyldiphenyl ether

2-hydroxybromobenzene

4-fluorobenzaldehyde

Downstream raw materials:

2-chloromethyldibenzofuran

dibenzofuran-2-carbaldehyde