Cobinamide, Co-aqua-,dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3), ion(1+), chloride (1:1)

Base Information

• Chemical Name: Cobinamide, Co-aqua-,dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3), ion(1+), chloride (1:1)
• CAS No.: 27085-12-7
• Molecular Formula: C62H90 Co N13 O15 P . Cl
• Molecular Weight: 1347.44
• Mol file: 27085-12-7.mol

Synonyms:Cobinamide,Co-aqua-, dihydrogen phosphate (ester), inner salt, 3'-ester with(5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3), ion(1+), chloride (9CI);Cobinamide, chloride hydroxide, monohydrate, dihydrogen phosphate (ester),inner salt, 3'-ester with 5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole; Cobinamide,chloride hydroxide, monohydrate, dihydrogen phosphate (ester), inner salt,3'-ester with 5,6-dimethyl-1-a-D-ribofuranosylbenzimidazole (8CI); Aquocobalamin chloride; Cobinamide,chloride, monohydrate, dihydrogen phosphate (ester), inner salt, 3'-ester with5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole

Chemical Property of Cobinamide, Co-aqua-,dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3), ion(1+), chloride (1:1)

Chemical Property:

• PSA: 444.21000
• LogP: 5.14330

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cobinamide, Co-aqua-,dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3), ion(1+), chloride (1:1)

There total 3 articles about Cobinamide, Co-aqua-,dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3), ion(1+), chloride (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

α-(2-oxo-1,3-dioxolan-4-yl)cobalamin → {Co(C20H6N4(CH3)8(CH2CH2CONH2)3(CH2CONH2)3(CH2CH2CONHCH2CH(CH3)OPO2OC4H8O3C9H9N2))(H2O)}(1+) (27085-12-7)

Guidance literature:

In water; Irradiation (UV/VIS); in presence of 2,2,6,6-tetramethylpiperidinyl-1-oxy (TEMPO), anaerobic irrdn. with a 275-W sunlamp for 95 s; air oxidn., HPLC;

Reference yield: 70.0%

α-(2-oxo-1,3-dioxolan-4-yl)cobalamin → vinylene carbonate (872-36-6) + {Co(C20H6N4(CH3)8(CH2CH2CONH2)3(CH2CONH2)3(CH2CH2CONHCH2CH(CH3)OPO2OC4H8O3C9H9N2))(H2O)}(1+) (27085-12-7)

Guidance literature:

In water; Irradiation (UV/VIS); in pH 7 phosphate buffer, aerobic irrdn. with a 275-W sunlamp, not stirred;

Reference yield: 18.0%

α-(2-oxo-1,3-dioxolan-4-yl)cobalamin → {Co(C20H6N4(CH3)8(CH2CH2CONH2)3(CH2CONH2)3(CH2CH2CONHCH2CH(CH3)OPO2OC4H8O3C9H9N2))(H2O)}(1+) (27085-12-7) + β-(2-oxo-1,3-dioxolan-4-yl)cobalamin

Guidance literature:

In water; Irradiation (UV/VIS); anaerobic irrdn. with a 275-W sunlamp for 70 s; air oxidn., HPLC (CH3CN/H2O);

Downstream raw materials:

cob(II)alamine