2,4-Imidazolidinedione, 3-(3-amino-1-oxopropyl)-1-(((5-(4-cyanophenyl)-2-furanyl)methylene)amino)-, monohydrochloride

Base Information

Chemical Name:2,4-Imidazolidinedione, 3-(3-amino-1-oxopropyl)-1-(((5-(4-cyanophenyl)-2-furanyl)methylene)amino)-, monohydrochloride
CAS No.:62452-10-2
Molecular Formula:C₁₈H₁₅N₅O₄*ClH
Molecular Weight:401.809
Hs Code.:

Synonyms:2,4-Imidazolidinedione, 3-(3-amino-1-oxopropyl)-1-(((5-(4-cyanophenyl)-2-furanyl)methylene)amino)-, monohydrochloride;62452-10-2;C18H15N5O4.ClH;C18-H15-N5-O4.Cl-H;LS-79061

Suppliers and Price of 2,4-Imidazolidinedione, 3-(3-amino-1-oxopropyl)-1-(((5-(4-cyanophenyl)-2-furanyl)methylene)amino)-, monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,4-Imidazolidinedione, 3-(3-amino-1-oxopropyl)-1-(((5-(4-cyanophenyl)-2-furanyl)methylene)amino)-, monohydrochloride

Chemical Property:

Vapor Pressure:1.68E-13mmHg at 25°C
Boiling Point:581.2°Cat760mmHg
Flash Point:305.3°C
Density:g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:401.0890817
Heavy Atom Count:28
Complexity:677

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)N(C(=O)N1N=CC2=CC=C(O2)C3=CC=C(C=C3)C#N)C(=O)CC[NH3+].[Cl-]
Isomeric SMILES:C1C(=O)N(C(=O)N1/N=C/C2=CC=C(O2)C3=CC=C(C=C3)C#N)C(=O)CC[NH3+].[Cl-]

Technology Process of 2,4-Imidazolidinedione, 3-(3-amino-1-oxopropyl)-1-(((5-(4-cyanophenyl)-2-furanyl)methylene)amino)-, monohydrochloride

There total 3 articles about 2,4-Imidazolidinedione, 3-(3-amino-1-oxopropyl)-1-(((5-(4-cyanophenyl)-2-furanyl)methylene)amino)-, monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [3-(3-{[1-[5-(4-Cyano-phenyl)-furan-2-yl]-meth-(E)-ylidene]-amino}-2,5-dioxo-imidazolidin-1-yl)-3-oxo-propyl]-carbamic acid tert-butyl ester

: 62452-10-2
4-(5-{[(E)-3-(3-Amino-propionyl)-2,4-dioxo-imidazolidin-1-ylimino]-methyl}-furan-2-yl)-benzonitrile; hydrochloride

Guidance literature:: With hydrogenchloride; acetic acid; at 15 ℃; for 5h; Yield given;
DOI:10.1002/jps.2600700933

Reference yield:

: 14663-27-5
4-{5-[(2,4-dioxo-imidazolidin-1-ylimino)-methyl]-furan-2-yl}-benzonitrile

: 62452-10-2
4-(5-{[(E)-3-(3-Amino-propionyl)-2,4-dioxo-imidazolidin-1-ylimino]-methyl}-furan-2-yl)-benzonitrile; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: ClCO₂CH₂CH(CH₃)2, Et₃N / dimethylformamide / 1.) -5 deg C to 0 deg C, 30 min, 2.) without cooling, 1 h

2: 3percent HCl, CH₃COOH / 5 h / 15 °C

With hydrogenchloride; acetic acid; triethylamine; isobutyl chloroformate; In N,N-dimethyl-formamide;
DOI:10.1002/jps.2600700933