Pyrenophorol

Base Information

Chemical Name:Pyrenophorol
CAS No.:22248-41-5
Molecular Formula:C₁₆H₂₄O₆
Molecular Weight:312.363
Hs Code.:
DSSTox Substance ID:DTXSID30448991
Wikidata:Q72503697
Metabolomics Workbench ID:127669
ChEMBL ID:CHEMBL2269362
Mol file:22248-41-5.mol

Synonyms:(5S,8R,13S,16R)-(-)-pyrenophorol;pyrenophorol

Suppliers and Price of Pyrenophorol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(-)-Pyrenophorol
100mg
$ 15840.00

Cayman Chemical
Pyrenophorol
1mg
$ 219.00

Total 6 raw suppliers

Chemical Property of Pyrenophorol

Chemical Property:

Melting Point:131 - 133 °C
PSA：93.06000
LogP:1.25800
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:0
Exact Mass:312.15728848
Heavy Atom Count:22
Complexity:388

Purity/Quality:

97% ^*data from raw suppliers

(-)-Pyrenophorol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCC(C=CC(=O)OC(CCC(C=CC(=O)O1)O)C)O
Isomeric SMILES:C[C@H]1OC(=O)/C=C/[C@H](CC[C@H](OC(=O)/C=C/[C@H](CC1)O)C)O
Description Pyrenophorol is a fungal metabolite that has been found in Alternaria and has diverse biological activities. It inhibits human topoisomerase II α when used at concentrations of 75 and 100 μM. It is active against S. cerevisiae (MIC = 4 μM) and M. violaceum. Pyrenophorol induces leaf necrosis and chlorophyll retention in wild oats when used at a concentration of 64 μM.
Uses The macrolide dilactone Pyrenophorol n anti-fungal antibiotic produced by the plant pathogenic fungi Pyrenophora avenue and Stemphylium radicinum, which is closely related structurally to (-)- Pyrenophorol Pyrenophorol is a simple macrocyclic dilactone produced by a number of species of pathogenic fungi, including Byssochlamys, Stenphyllum, Alternaria and Drechslera, first reported in the late 1960s. Pyrenophorol exhibits antibiotic, herbicidal and anthelmintic properties, and is a weak inhibitor of propyl endopeptidases. Pyrenophorol inhibits seed germination but once the seed is germinated, pyrenophlorol enhances root development but causes abnormal chlorophyll retention in leaf sections. The macrolide dilactone Pyrenophorol was originally isolated from Byssochlamys niveah and Stemphylium radicinum. Pyrenophorol was moderately active against the fungus Microbotryum violaceum. It is an anti-fungal antibiotic produced by the plant pathogenic fungi Pyrenophora avenue and Stemphylium radicinum, which is closely related structurally to (-)-Pyrenophorol.

Technology Process of Pyrenophorol

There total 90 articles about Pyrenophorol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%