2-(4-(2-Propylthio)phenyl)propionamide

Base Information

Chemical Name:2-(4-(2-Propylthio)phenyl)propionamide
CAS No.:129602-95-5
Molecular Formula:C₁₂H₁₇NOS
Molecular Weight:223.339
Hs Code.:
DSSTox Substance ID:DTXSID30926446
Mol file:129602-95-5.mol

Synonyms:129602-95-5;2-(4-(2-Propylthio)phenyl)propionamide;2-(4-propan-2-ylsulfanylphenyl)propanamide;BRN 4182752;alpha-Methyl-4-((1-methylethyl)thio)benzeneacetamide;Benzeneacetamide, alpha-methyl-4-((1-methylethyl)thio)-;DTXSID30926446;AKOS005066346;LS-28572;2-{4-[(Propan-2-yl)sulfanyl]phenyl}propanimidic acid

Suppliers and Price of 2-(4-(2-Propylthio)phenyl)propionamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ALPHA-METHYL-4-((1-METHYLETHYL)THIO)BENZENEACETAMIDE 95.00%
5MG
$ 502.44

Total 1 raw suppliers

Chemical Property of 2-(4-(2-Propylthio)phenyl)propionamide

Chemical Property:

Vapor Pressure:2.28E-06mmHg at 25°C
Boiling Point:392.5°Cat760mmHg
Flash Point:191.2°C
PSA：69.38000
Density:1.09g/cm³
LogP:3.92560
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:223.10308534
Heavy Atom Count:15
Complexity:210

Purity/Quality:: ALPHA-METHYL-4-((1-METHYLETHYL)THIO)BENZENEACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)SC1=CC=C(C=C1)C(C)C(=O)N

Technology Process of 2-(4-(2-Propylthio)phenyl)propionamide

There total 9 articles about 2-(4-(2-Propylthio)phenyl)propionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3019-20-3
isopropylthiobenzene

: 129602-95-5
2-(4-(2-propylthio)phenyl)propionamide

Guidance literature:: Multi-step reaction with 6 steps

1: 27 percent / AlCl₃ / 1,2-dichloro-ethane / 4.5 h / 20 °C

2: diethyl ether; toluene / 3 h / Ambient temperature

3: K₂CO₃ / methanol; H₂O / 6 h / Heating

4: 95 percent / red phosphorus, I₂ / aq. acetic acid / 5 h / Heating

5: SOCl₂ / hexane / 4 h / Heating

6: NH₃ / diethyl ether / Ambient temperature

With phosphorus; aluminium trichloride; thionyl chloride; ammonia; iodine; potassium carbonate; In methanol; diethyl ether; hexane; water; acetic acid; 1,2-dichloro-ethane; toluene;

Reference yield:

: 59430-62-5
2-(4-aminophenyl)propionic acid

: 129602-95-5
2-(4-(2-propylthio)phenyl)propionamide

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) aq. HCl, NaNO₂ / 1.) water, 0 deg C, 45 min, 2.) ethyl acetate, 55 deg C, 30 min

2: KOH / ethanol; H₂O / 12 h / Heating

3: 1.) K₂CO₃, 2.) NaOH / 1.) DMF, 60 deg C, 5 h, 2.) ethanol/water, reflux, 5.5 h

4: SOCl₂ / hexane / 4 h / Heating

5: NH₃ / diethyl ether / Ambient temperature

With hydrogenchloride; potassium hydroxide; sodium hydroxide; thionyl chloride; ammonia; potassium carbonate; sodium nitrite; In diethyl ether; ethanol; hexane; water;

Reference yield:

: 34124-56-6
2-(4-mercaptophenyl)propionic acid

: 129602-95-5
2-(4-(2-propylthio)phenyl)propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) K₂CO₃, 2.) NaOH / 1.) DMF, 60 deg C, 5 h, 2.) ethanol/water, reflux, 5.5 h

2: SOCl₂ / hexane / 4 h / Heating

3: NH₃ / diethyl ether / Ambient temperature

With sodium hydroxide; thionyl chloride; ammonia; potassium carbonate; In diethyl ether; hexane;