Technology Process of 17-acetyl-6-chloro-17-hydroxy-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one
There total 5 articles about 17-acetyl-6-chloro-17-hydroxy-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogenchloride; acetic acid;
at 20 - 45 ℃;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium carbonate / water; methanol / 20 - 45 °C
2.1: magnesium / tetrahydrofuran / 30 - 35 °C
2.2: 50 - 55 °C
2.3: 50 - 55 °C / pH 2 - 3
3.1: Perbenzoic acid / ethyl acetate / 20 - 25 °C
4.1: acetic acid; hydrogenchloride / 20 - 45 °C
With
hydrogenchloride; Perbenzoic acid; sodium carbonate; magnesium; acetic acid;
In
tetrahydrofuran; methanol; water; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: magnesium / tetrahydrofuran / 30 - 35 °C
1.2: 50 - 55 °C
1.3: 50 - 55 °C / pH 2 - 3
2.1: Perbenzoic acid / ethyl acetate / 20 - 25 °C
3.1: acetic acid; hydrogenchloride / 20 - 45 °C
With
hydrogenchloride; Perbenzoic acid; magnesium; acetic acid;
In
tetrahydrofuran; ethyl acetate;