1-(2,2'-Bithiophen-5-yl)methanamine

Base Information

Chemical Name:1-(2,2'-Bithiophen-5-yl)methanamine
CAS No.:4380-96-5
Molecular Formula:C9H9 N S2
Molecular Weight:195.3
Hs Code.:2934999090
European Community (EC) Number:822-923-5
DSSTox Substance ID:DTXSID50380066
Wikidata:Q27096009
Metabolomics Workbench ID:150278
ChEMBL ID:CHEMBL538940
Mol file:4380-96-5.mol

Synonyms:4380-96-5;2,2'-bithiophene-5-methylamine;2,2'-bithiophen-5-ylmethanamine;[2,2'-Bithiophen]-5-ylmethanamine;1-(2,2'-bithiophen-5-yl)methanamine;(5-thiophen-2-ylthiophen-2-yl)methanamine;CHEMBL538940;(5-(2-thienyl)-2-thienyl)methylamine;SDCCGMLS-0065983.P001;C-[2,2']Bithiophenyl-5-yl-methylamine;D0R7BT;SCHEMBL2690127;DTXSID50380066;FHYTVXBZSXZMGD-UHFFFAOYSA-N;2,2''-bithiophen-5-ylmethanamine;BDBM50294164;MFCD00110111;AKOS006227622;DB07094;1-(2,2''-bithiophen-5-yl)methanamine;BS-28548;PD006111;1-([2,2'-Bithiophen]-5-yl)methanamine;(5-thiophen-2-ylthiophen-2-yl)methylamine;CS-0206120;FT-0609198;c-[2,2']bithiophenyl-5-yl-methylamine, AldrichCPR;J-506780;Q27096009

Suppliers and Price of 1-(2,2'-Bithiophen-5-yl)methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
5-(Aminomethyl)-[2,2']-bithiophene
250 mg
$ 304.00

SynQuest Laboratories
5-(Aminomethyl)-[2,2']-bithiophene
1 g
$ 880.00

Matrix Scientific
2,2'-Bithiophen-5-ylmethanamine 95%
25g
$ 3652.00

Matrix Scientific
2,2'-Bithiophen-5-ylmethanamine 95%
5g
$ 1218.00

Crysdot
[2,2'-Bithiophen]-5-ylmethanamine 95+%
5g
$ 707.00

Chemenu
2,2''-Bithiophen-5-ylmethanamine 95%
1g
$ 589.00

Arctom
[2,2'-Bithiophen]-5-ylmethanamine 98%
250mg
$ 182.00

Arctom
[2,2'-Bithiophen]-5-ylmethanamine 98%
1g
$ 525.00

Apolloscientific
5-(Aminomethyl)-[2,2']-bithiophene 95%
250mg
$ 276.00

Apolloscientific
5-(Aminomethyl)-[2,2']-bithiophene 95%
1g
$ 798.00

Total 12 raw suppliers

Chemical Property of 1-(2,2'-Bithiophen-5-yl)methanamine

Chemical Property:

Melting Point:71-73oC
Boiling Point:128 °C
Flash Point:141.6oC
PSA：82.50000
Density:1.27 g/cm3
LogP:3.63560
Storage Temp.:2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:195.01764164
Heavy Atom Count:12
Complexity:152

Purity/Quality:

99% ^*data from raw suppliers

5-(Aminomethyl)-[2,2']-bithiophene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C,T
Statements: 34-25
Safety Statements: 26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CSC(=C1)C2=CC=C(S2)CN

Technology Process of 1-(2,2'-Bithiophen-5-yl)methanamine

There total 5 articles about 1-(2,2'-Bithiophen-5-yl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 632338-98-8
[4-(thien-2-yl)-thien-2-yl]methylazide

: 4380-96-5
[5-(thiophen-2-yl)thiophen-2-yl]methanamine

Guidance literature:: With water; triphenylphosphine; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2005.02.002

Reference yield:

: 256327-11-4
N-[2,2']bithiophenyl-5-ylmethyl-phthalamic acid

: 4380-96-5
[5-(thiophen-2-yl)thiophen-2-yl]methanamine

Guidance literature:: With ethylenediamine; In 1,4-dioxane; propan-1-ol; water; for 24h; Reflux;
DOI:10.1021/ol301037s

Reference yield:

: 3480-11-3
5-bromo(2,2'-bithiophene)

: 4380-96-5
[5-(thiophen-2-yl)thiophen-2-yl]methanamine

Guidance literature:: Multi-step reaction with 2 steps

1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; sodium carbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾ / 1,4-dioxane; water / 36 h / Reflux

2: ethylenediamine / 1,4-dioxane; propan-1-ol; water / 24 h / Reflux

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; sodium carbonate; ethylenediamine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In 1,4-dioxane; propan-1-ol; water; 1: Suzuki-miyaura coupling;
DOI:10.1021/ol301037s