2-Methyl-1-morpholinopropan-2-amine

Base Information

• Chemical Name: 2-Methyl-1-morpholinopropan-2-amine
• CAS No.: 6105-75-5
• Molecular Formula: C8H18 N2 O
• Molecular Weight: 158.244
• Hs Code.: 2934999090
• European Community (EC) Number: 691-134-4
• DSSTox Substance ID: DTXSID80209933
• Nikkaji Number: J41.771H
• Mol file: 6105-75-5.mol

Synonyms:2-Methyl-1-morpholinopropan-2-amine;6105-75-5;1,1-Dimethyl-2-morpholin-4-yl-ethylamine;2-methyl-1-morpholino-2-propanamine;2-methyl-1-(morpholin-4-yl)propan-2-amine;4-(2-Amino-2-methylpropyl)morpholine;2-methyl-1-morpholin-4-ylpropan-2-amine;Morpholine, 4-(2-amino-2-methylpropyl)-;Morpholine, N-(2-aminoisobutyl)-;4-Morpholineethanamine, a,a-dimethyl-;BRN 0106002;4-27-00-00438 (Beilstein Handbook Reference);(1,1-dimethyl-2-morpholin-4-ylethyl)amine;4-morpholineethanamine, alpha,alpha-dimethyl-;SCHEMBL862113;AMY6396;DTXSID80209933;BBL041079;MFCD01714129;STK503352;4-(2-amino-2-methyl)propylmorpholine;AKOS000302510;NCGC00374308-01;1,1-dimethyl-2-morpholin-4-ylethylamine;AS-30725;LS-92410;2-Methyl-1-(4-morpholinyl)-2-propanamine;2-methyl-1-(morpholin-4-yl)-2-propylamine;CS-0001049;FT-0651423;A25684;EN300-230322;4-Morpholineethanamine, .alpha.,.alpha.-dimethyl-;(1,1-Dimethyl-2-morpholin-4-ylethyl)amine AldrichCPR;(1,1-Dimethyl-2-morpholin-4-ylethyl)amine, AldrichCPR;Z336080124

Chemical Property of 2-Methyl-1-morpholinopropan-2-amine

Chemical Property:

• Vapor Pressure: 0.077mmHg at 25°C
• Boiling Point: 227.6 °C at 760 mmHg
• Flash Point: 91.4 °C
• PSA: 38.49000
• Density: 0.971 g/cm³
• LogP: 0.69410
• Storage Temp.: 2-8°C
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 158.141913202
• Heavy Atom Count: 11
• Complexity: 119

Purity/Quality:

97% ^*data from raw suppliers

1,1-Dimethyl-2-morpholin-4-ylethylamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C,Xi
• Statements: 34
• Safety Statements: 23-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(CN1CCOCC1)N

Technology Process of 2-Methyl-1-morpholinopropan-2-amine

There total 4 articles about 2-Methyl-1-morpholinopropan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-(2-methyl-2-nitropropyl)morpholine (33453-98-4) → 2-methyl-1-(morpholin-4-yl)propan-2-amine (6105-75-5)

Guidance literature:

With hydrogen; In methanol; at 20 ℃; for 0.1h;

Reference yield:

C8H16N2O3*ClH → 2-methyl-1-(morpholin-4-yl)propan-2-amine (6105-75-5)

Guidance literature:

With hydrogen; nickel; In methanol; at 35 ℃; for 0.666667h; under 2585.81 Torr;

Reference yield:

morpholine (110-91-8,99108-56-2) + 2,2-dimethylaziridine (2658-24-4) → 2-methyl-1-(morpholin-4-yl)propan-2-amine (6105-75-5)

Guidance literature:

With ammonium chloride;

DOI:10.1021/ja01181a053

upstream raw materials:

morpholine

2,2-dimethylaziridine

4-(2-methyl-2-nitropropyl)morpholine

Downstream raw materials:

5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(2-methyl-1-morpholinopropan-2-yl)-1H-pyrazole-3-carboxamide

N-(2-methyl-1-morpholinopropan-2-yl)-2-(pyridin-3-ylmethylthio)benzamide