1,2,3,4,6,7,12,12b-Octahydro-12,12b-dimethyl-3-ethyl-indolo(2,3-a)quinolizine

Base Information

Chemical Name:1,2,3,4,6,7,12,12b-Octahydro-12,12b-dimethyl-3-ethyl-indolo(2,3-a)quinolizine
CAS No.:82605-36-5
Molecular Formula:C₁₉H₂₆N₂
Molecular Weight:282.429
Hs Code.:
DSSTox Substance ID:DTXSID001002815
Nikkaji Number:J68.763D

Synonyms:1,2,3,4,6,7,12,12b-Octahydro-12,12b-dimethyl-3-ethyl-indolo(2,3-a)quinolizine;Indolo(2,3-a)quinolizine, 1,2,3,4,6,7,12,12b-octahydro-12,12b-dimethyl-3-ethyl-;82605-36-5;DTXSID001002815;LS-83920;1,2,3,4,6,7,12,12b-Octahydro-12,12b-dimethyl-3-ethylindolo[2,3-a]quinolizine;3-Ethyl-12,12b-dimethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine

Suppliers and Price of 1,2,3,4,6,7,12,12b-Octahydro-12,12b-dimethyl-3-ethyl-indolo(2,3-a)quinolizine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1,2,3,4,6,7,12,12b-Octahydro-12,12b-dimethyl-3-ethyl-indolo(2,3-a)quinolizine

Chemical Property:

Vapor Pressure:4.87E-07mmHg at 25°C
Boiling Point:413.3°Cat760mmHg
Flash Point:203.7°C
Density:1.13g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:282.209598838
Heavy Atom Count:21
Complexity:395

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1CCC2(C3=C(CCN2C1)C4=CC=CC=C4N3C)C

Technology Process of 1,2,3,4,6,7,12,12b-Octahydro-12,12b-dimethyl-3-ethyl-indolo(2,3-a)quinolizine

There total 4 articles about 1,2,3,4,6,7,12,12b-Octahydro-12,12b-dimethyl-3-ethyl-indolo(2,3-a)quinolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.5%

: 82605-28-5
3-Ethyl-12,12b-dimethyl-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-4-one

: 82605-36-5
3-Ethyl-12,12b-dimethyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; for 20h; Heating;
DOI:10.1007/BF00762054

Reference yield:

: 10297-79-7
3-ethyl-6-methyl-3,4-dihydro-2H-pyran-2-one

: 82605-36-5
3-Ethyl-12,12b-dimethyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizine

Guidance literature:: Multi-step reaction with 3 steps

1: 70.3 percent / benzene / 22 h / Heating

2: 81 percent / aq. HCl / methanol / Heating

3: 74.5 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 20 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; methanol; diethyl ether; benzene;
DOI:10.1007/BF00762054

Reference yield:

: 82605-20-7
2-Ethyl-5-oxo-hexanoic acid [2-(1-methyl-1H-indol-3-yl)-ethyl]-amide

: 82605-36-5
3-Ethyl-12,12b-dimethyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizine

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / aq. HCl / methanol / Heating

2: 74.5 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 20 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; In tetrahydrofuran; methanol; diethyl ether;
DOI:10.1007/BF00762054