Piperidine, 1-((1-phenylcyclopentyl)carbonyl)-

Base Information

• Chemical Name: Piperidine, 1-((1-phenylcyclopentyl)carbonyl)-
• CAS No.: 102207-07-8
• Molecular Formula: C₁₇H₂₃NO
• Molecular Weight: 257.376
• DSSTox Substance ID: DTXSID20144773
• Nikkaji Number: J83.590K
• Wikidata: Q83009034
• ChEMBL ID: CHEMBL1084735
• Mol file: 102207-07-8.mol

Synonyms:Piperidine, 1-((1-phenylcyclopentyl)carbonyl)-;102207-07-8;1-(1-Phenylcyclopentanecarbonyl)piperidine;(1-phenylcyclopentyl)-piperidin-1-ylmethanone;1-[(1-phenylcyclopentyl)carbonyl]piperidine;SCHEMBL6896465;CHEMBL1084735;DTXSID20144773;STK179625;AKOS000543667;(1-phenylcyclopentyl)(piperidin-1-yl)methanone;AG-690/12893998;SR-01000313026;SR-01000313026-1

Chemical Property of Piperidine, 1-((1-phenylcyclopentyl)carbonyl)-

Chemical Property:

• Vapor Pressure: 3.52E-07mmHg at 25°C
• Boiling Point: 417.5°Cat760mmHg
• Flash Point: 170.1°C
• Density: 1.089g/cm³
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 257.177964357
• Heavy Atom Count: 19
• Complexity: 307

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)C(=O)C2(CCCC2)C3=CC=CC=C3

Technology Process of Piperidine, 1-((1-phenylcyclopentyl)carbonyl)-

There total 6 articles about Piperidine, 1-((1-phenylcyclopentyl)carbonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclopentanecarboxylic acid (3400-45-1) → C17H23NO (102207-07-8)

Guidance literature:

Multi-step reaction with 6 steps

1: tetrahydrofuran / 10 h / Reflux

2: boron trifluoride diethyl etherate / dichloromethane / 1 h / 20 °C

3: methanol; N-Bromosuccinimide / Reflux

4: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride

5: potassium carbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / Reflux

6: Reflux

With methanol; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); boron trifluoride diethyl etherate; tri-n-butyl-tin hydride; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; 5: Baeyer-Villiger oxidation;

DOI:10.1002/jccs.201190135

Reference yield:

phenyl(1-phenylcyclopentyl)methanone (41848-73-1) → C17H23NO (102207-07-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / Reflux

2: Reflux

With potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; 1: Baeyer-Villiger oxidation;

DOI:10.1002/jccs.201190135

Reference yield:

6,6-diphenylfulvene (7714-72-9) → C17H23NO (102207-07-8)

Guidance literature:

Multi-step reaction with 4 steps

1: methanol; N-Bromosuccinimide / Reflux

2: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride

3: potassium carbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / Reflux

4: Reflux

With methanol; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; 3: Baeyer-Villiger oxidation;

DOI:10.1002/jccs.201190135

upstream raw materials:

piperidine

cyclopentanecarboxylic acid

6,6-diphenylfulvene

phenyl(1-phenylcyclopentyl)methanone