Methanone, (1-bromo-2-(4-fluorophenyl)-3-indolizinyl)(3-bromo-4-hydroxyphenyl)-

Base Information

Chemical Name:Methanone, (1-bromo-2-(4-fluorophenyl)-3-indolizinyl)(3-bromo-4-hydroxyphenyl)-
CAS No.:77832-84-9
Molecular Formula:C21H12Br2FNO2
Molecular Weight:489.1319
Hs Code.:
DSSTox Substance ID:DTXSID30228457
Wikidata:Q83108443

Synonyms:1-Bromo-2-(4-fluorophenyl)-3-(3-bromo-4-hydroxybenzoyl)indolizine;Methanone, (1-bromo-2-(4-fluorophenyl)-3-indolizinyl)(3-bromo-4-hydroxyphenyl)-;(1-Bromo-2-(4-fluorophenyl)-3-indolizinyl)(3-bromo-4-hydroxyphenyl)methanone;77832-84-9;C21H12Br2FNO2;SCHEMBL11190130;DTXSID30228457;C21-H12-Br2-F-N-O2;LS-91140

Suppliers and Price of Methanone, (1-bromo-2-(4-fluorophenyl)-3-indolizinyl)(3-bromo-4-hydroxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methanone, (1-bromo-2-(4-fluorophenyl)-3-indolizinyl)(3-bromo-4-hydroxyphenyl)-

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.68g/cm³
XLogP3:6.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:488.91983
Heavy Atom Count:27
Complexity:542

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=C(N2C=C1)C(=O)C3=CC(=C(C=C3)O)Br)C4=CC=C(C=C4)F)Br

Technology Process of Methanone, (1-bromo-2-(4-fluorophenyl)-3-indolizinyl)(3-bromo-4-hydroxyphenyl)-

There total 2 articles about Methanone, (1-bromo-2-(4-fluorophenyl)-3-indolizinyl)(3-bromo-4-hydroxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Toluene-4-sulfonic acid 2-bromo-4-[1-bromo-2-(4-fluoro-phenyl)-indolizine-3-carbonyl]-phenyl ester

: 77832-84-9
1-bromo-2-(4-fluoro-phenyl)-3-(3-bromo-4-hydroxy-benzoyl)-indolizine

Guidance literature:: With sodium hydroxide; In methanol; acetone; for 21h; Heating;

Reference yield:

: 88273-80-7
Toluene-4-sulfonic acid 2-bromo-4-[2-(4-fluoro-phenyl)-indolizine-3-carbonyl]-phenyl ester

: 77832-84-9
1-bromo-2-(4-fluoro-phenyl)-3-(3-bromo-4-hydroxy-benzoyl)-indolizine

Guidance literature:: Multi-step reaction with 2 steps

1: Br₂, sodium acetate trihydrate / dioxane / 1.5 h / 20 - 30 °C

2: 30percent sodium hydroxide / methanol; acetone / 21 h / Heating

With sodium hydroxide; bromine; sodium acetate; In 1,4-dioxane; methanol; acetone;