N'-[[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]propanediamide

Base Information

Chemical Name:N'-[[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]propanediamide
CAS No.:18612-36-7
Molecular Formula:C₂₃H₂₂Cl₃N₅O₂S
Molecular Weight:538.885
Hs Code.:
DSSTox Substance ID:DTXSID50940043

Synonyms:18612-36-7;DTXSID50940043;3-[({4-[Bis(2-chloroethyl)amino]phenyl}methylidene)hydrazinylidene]-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-hydroxypropanimidic acid

Suppliers and Price of N'-[[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]propanediamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N'-[[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]propanediamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.4g/cm³
XLogP3:5.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:537.055979
Heavy Atom Count:34
Complexity:667

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C=NNC(=O)CC(=O)NC2=NC(=CS2)C3=CC=C(C=C3)Cl)N(CCCl)CCCl

Technology Process of N'-[[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]propanediamide

There total 2 articles about N'-[[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]propanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18612-27-6
N-[4-(4-chloro-phenyl)-thiazol-2-yl]-malonamic acid ethyl ester

: 18612-36-7
N-[4-(4-chloro-phenyl)-thiazol-2-yl]-malonamic acid {4-[bis-(2-chloro-ethyl)-amino]-benzylidene}-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: N₂H₄*H₂O / ethanol / 0.17 h / Heating

2: ethanol / 70 °C

With hydrazine hydrate; In ethanol;
DOI:10.1021/jm00307a037