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Nisin

Base Information Edit
  • Chemical Name:Nisin
  • CAS No.:1414-45-5
  • Molecular Formula:C143H230N42O37S7
  • Molecular Weight:3354.25
  • Hs Code.:
  • Mol file:1414-45-5.mol
Nisin

Synonyms:1-Thia-4,7,10,13,16,19-hexaazacyclodocosane, cyclic peptide deriv.;1H,9H-Pyrrolo[2,1-i][1,4,7,10]thiatriazacyclotridecine, cyclic peptide deriv.;9,19-Dithia-2,5,13,16,22-pentaazabicyclo[9.9.2]docosane, cyclic peptide deriv.;Ambicin N;Delvoplus;MicroGARD MG 300;Nisaplin;Nisin(1-34);Nisitrol;Novasin;NisinA (9CI);

Suppliers and Price of Nisin
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Nisin
  • 100g
  • $ 360.00
  • TRC
  • NisinA,Technicalgrade(~2.5%mainlysodiumchlorideanddenaturedmilksolids)
  • 10 g
  • $ 200.00
  • Sigma-Aldrich
  • Nisin from Lactococcus lactis 2.5% (balance sodium chloride and denatured milk solids)
  • 25g
  • $ 531.00
  • Sigma-Aldrich
  • Nisin from Lactococcus lactis 2.5% (balance sodium chloride and denatured milk solids)
  • 5g
  • $ 156.00
  • Sigma-Aldrich
  • Nisin from Lactococcus lactis 2.5% (balance sodium chloride and denatured milk solids)
  • 1g
  • $ 59.40
  • Sigma-Aldrich
  • Nisin Ready Made Solution (20,000-40,000 IU/mL in 0.02N HCl)
  • 1ml
  • $ 97.80
  • ChemScene
  • Nisin
  • 1g
  • $ 90.00
  • ChemScene
  • Nisin
  • 500mg
  • $ 70.00
  • ChemScene
  • Nisin
  • 100mg
  • $ 50.00
  • ChemScene
  • Nisin
  • 5g
  • $ 120.00
Total 162 raw suppliers
Chemical Property of Nisin Edit
Chemical Property:
  • Appearance/Colour:grey or white or light yellow powder 
  • Refractive Index:1.635 
  • Boiling Point:2966.771 °C at 760 mmHg 
  • Flash Point:1748.039 °C 
  • PSA:1390.67000 
  • Density:1.402 g/cm3 
  • LogP:3.42180 
  • Storage Temp.:2-8°C 
  • Solubility.:insoluble in H2O; insoluble in EtOH; ≥5.63 mg/mL in DMSO with gentle warming and ultrasonic 
  • Water Solubility.:Soluble in water 
Purity/Quality:

99% *data from raw suppliers

Nisin *data from reagent suppliers

Safty Information:
  • Pictogram(s): HarmfulXn 
  • Hazard Codes:Xn 
  • Statements: 22-36/37/38 
  • Safety Statements: 22-24/25-36-26 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Description As a ribosomally synthesized peptide, Nisin has broad-spectrum antibacterial activity that is produced by the Lactococcus lactis. In the food industry, Nisin is obtained from the cultivating of Lactococcus lactis on natural substrates, such as milk or dextrose. It serves as a natural, antibacterial, and toxicologically safe food preservative which is protect against many bacteria that are food-spoilage pathogens. As a food additive, Nisin is popularly used in food production, such as milk, meats, fast food, beverages, health care products and medicines, etc. It is effective to decrease sterilization time, lower temperature during food sterilization, improve food quality, lessen damage to nutrition, and extend shelf life by suppressing Gram-positive spoilage and pathogenic bacteria. Besides, it has been studied as a possible treatment for infections of Clostridium difficile combined with miconazole. It was originally isolated in the late 1930s and approved as an additive for food use in the USA in the late 1960s. Nisin functions by binding to cell wall precursor lipid components of bacteria and disrupts cell wall production. Once introduced Nisin initially blends with Lipid II, a precursor molecule used to form bacterial cell wall, to create a complex. The complex penetrates the cell wall and breaks into the cytoplasmic membrane and form pores, through which the internal cytoplasmic content oozes out leading to bacterial inhibition or death.
  • Uses Nisin is an antimicrobial agent derived from pure culture fermenta- tions of certain strains of streptococcus lactis lancefield group n. nisin preparation contains nisin, a group of related peptides with antibiotic activity. it is used to inhibit the outgrowth of clostridium botulinum spores and toxin formation in pasteurized cheese spreads and pasteurized process cheese spreads; pasteurized cheese spread with fruits, vegetables, or meats; and pasteurized process cheese spread with fruits, vegetables, or meats. Nisin is a particularly effective bacteriosin against C. botulinum, is allowed in processed cheese food. An antibiotic with bactericidal action
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