(5S)-3,4,5-Trimethyl-5,6,7,8-tetrahydronaphtho[2,3-b]furan-9-ol

Base Information

Chemical Name:(5S)-3,4,5-Trimethyl-5,6,7,8-tetrahydronaphtho[2,3-b]furan-9-ol
CAS No.:24393-79-1
Molecular Formula:C₁₅H₁₈O₂
Molecular Weight:230.307
Hs Code.:
Mol file:24393-79-1.mol

Synonyms:Cacalol(7CI); Naphtho[2,3-b]furan-9-ol, 5,6,7,8-tetrahydro-3,4,5-trimethyl-, (S)-(8CI)

Suppliers and Price of (5S)-3,4,5-Trimethyl-5,6,7,8-tetrahydronaphtho[2,3-b]furan-9-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of (5S)-3,4,5-Trimethyl-5,6,7,8-tetrahydronaphtho[2,3-b]furan-9-ol

Chemical Property:

Vapor Pressure:4.2E-06mmHg at 25°C
Boiling Point:373.3°Cat760mmHg
Flash Point:179.6°C
PSA：33.37000
Density:1.128g/cm³
LogP:4.19500

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (5S)-3,4,5-Trimethyl-5,6,7,8-tetrahydronaphtho[2,3-b]furan-9-ol

There total 14 articles about (5S)-3,4,5-Trimethyl-5,6,7,8-tetrahydronaphtho[2,3-b]furan-9-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 64185-49-5
(S)-9-methoxy-5,6,7,8-tetrahydro-3,4,5-trimethylnaphtho[2,3,-b]furan

: 24393-79-1,67832-21-7
Cacalol

Guidance literature:: With boron tribromide; In dichloromethane; at -78 - 0 ℃; for 1.5h;
DOI:10.3987/COM-04-10262

Reference yield:

: 849435-22-9
(S)-methyl 4-(2'-methyl-4',5'-dimethoxyphenyl)pentanoate

: 24393-79-1,67832-21-7
Cacalol

Guidance literature:: Multi-step reaction with 9 steps

1: 100 percent / NaOH / tetrahydrofuran; H₂O; methanol / 2 h / 20 °C

2: 86 percent / P₂O₅; methanesulfonic acid / 1.5 h / 20 °C

3: 94 percent / H₂; acetic acid / 20 percent Pd(OH)2-C / tetrahydrofuran / 1.5 h / 20 °C / 760 Torr

4: 68 percent / AlCl₃; AgClO₄ / CH₂Cl₂ / 2 h / 20 °C

5: AlCl₃ / benzene / 1.5 h / 20 °C

6: 96 percent / K₂CO₃ / dimethylformamide / 2.5 h / 50 °C

7: 98 percent / NaOH / tetrahydrofuran; H₂O; methanol / 1.5 h / 20 °C

8: 70 percent / sodium acetate / acetic anhydride / 1.5 h / 100 °C

9: 60 percent / BBr₃ / CH₂Cl₂ / 1.5 h / -78 - 0 °C

With sodium hydroxide; aluminium trichloride; methanesulfonic acid; hydrogen; sodium acetate; silver perchlorate; phosphorus pentoxide; boron tribromide; potassium carbonate; acetic acid; palladium hydroxide - carbon; In tetrahydrofuran; methanol; dichloromethane; water; acetic anhydride; N,N-dimethyl-formamide; benzene; 4: Mukaiyama's Friedel-Crafts acylation;
DOI:10.3987/COM-04-10262

Reference yield:

: 849435-23-0
(S)-7,8-dimethoxy-4,5-dimethyl-1-tetralone

: 24393-79-1,67832-21-7
Cacalol

Guidance literature:: Multi-step reaction with 7 steps

1: 94 percent / H₂; acetic acid / 20 percent Pd(OH)2-C / tetrahydrofuran / 1.5 h / 20 °C / 760 Torr

2: 68 percent / AlCl₃; AgClO₄ / CH₂Cl₂ / 2 h / 20 °C

3: AlCl₃ / benzene / 1.5 h / 20 °C

4: 96 percent / K₂CO₃ / dimethylformamide / 2.5 h / 50 °C

5: 98 percent / NaOH / tetrahydrofuran; H₂O; methanol / 1.5 h / 20 °C

6: 70 percent / sodium acetate / acetic anhydride / 1.5 h / 100 °C

7: 60 percent / BBr₃ / CH₂Cl₂ / 1.5 h / -78 - 0 °C

With sodium hydroxide; aluminium trichloride; hydrogen; sodium acetate; silver perchlorate; boron tribromide; potassium carbonate; acetic acid; palladium hydroxide - carbon; In tetrahydrofuran; methanol; dichloromethane; water; acetic anhydride; N,N-dimethyl-formamide; benzene; 2: Mukaiyama's Friedel-Crafts acylation;
DOI:10.3987/COM-04-10262