5-(1-methyl-1H-benzimidazol-2-yl)-1,3,4-oxadiazol-2(3H)-one

Base Information

Chemical Name:5-(1-methyl-1H-benzimidazol-2-yl)-1,3,4-oxadiazol-2(3H)-one
CAS No.:78620-28-7
Molecular Formula:C₁₀H₈N₄O₂
Molecular Weight:216.199
Hs Code.:

Synonyms:1-Methyl-2-(1,3,4-oxadiazol-2(3H)-one-5-yl)benzimidazole;1-Methyl-2-(2-oxo-3H-1,3,4-oxadiazol-5-yl)-benzimidazole;5-(1-Methyl-1H-benzoimidazol-2-yl)-3H-[1,3,4]oxadiazol-2-one;

Suppliers and Price of 5-(1-methyl-1H-benzimidazol-2-yl)-1,3,4-oxadiazol-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(1-methyl-1H-benzimidazol-2-yl)-1,3,4-oxadiazol-2(3H)-one

Chemical Property:

PSA：76.71000
Density:1.59g/cm³
LogP:0.91660

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(1-methyl-1H-benzimidazol-2-yl)-1,3,4-oxadiazol-2(3H)-one

There total 3 articles about 5-(1-methyl-1H-benzimidazol-2-yl)-1,3,4-oxadiazol-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: 78620-27-6
ethyl 3-(1-methyl-2-benzimidazolyl)hydrazinecarboxylate

: 78620-28-7
1-methyl-2-(2,3-dihydro-2-oxo-1,3,4-oxadiazol-5-yl)benzimidazole

Guidance literature:: at 180 ℃; for 0.5h;
DOI:10.1021/jm00368a004

Reference yield:

: 14468-46-3
1-methyl-2-(trichloromethyl)benzimidazole

: 78620-28-7
1-methyl-2-(2,3-dihydro-2-oxo-1,3,4-oxadiazol-5-yl)benzimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 49 percent / NaHCO₃ / acetonitrile; H₂O / 1 h / Heating

2: 22 percent / 0.5 h / 180 °C

With sodium hydrogencarbonate; In water; acetonitrile;
DOI:10.1021/jm00368a004