1-methyl-4-(morpholin-4-yl)-3-nitroquinolin-2(1H)-one

Base Information

Chemical Name:1-methyl-4-(morpholin-4-yl)-3-nitroquinolin-2(1H)-one
CAS No.:141945-55-3
Molecular Formula:C₁₄H₁₅N₃O₄
Molecular Weight:289.291
Hs Code.:
DSSTox Substance ID:DTXSID90931273
Nikkaji Number:J466.318G
Wikidata:Q82906827
Mol file:141945-55-3.mol

Synonyms:1-methyl-4-(morpholin-4-yl)-3-nitroquinolin-2(1H)-one;Cambridge id 5710623;Oprea1_021188;141945-55-3;DTXSID90931273;STK851740;AKOS000629764;AB00094342-01;1-Methyl-3-nitro-4-morpholinoquinolin-2(1H)-one;Z275481396;5710-62-3

Suppliers and Price of 1-methyl-4-(morpholin-4-yl)-3-nitroquinolin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-methyl-4-(morpholin-4-yl)-3-nitroquinolin-2(1H)-one

Chemical Property:

Vapor Pressure:1.21E-06mmHg at 25°C
Boiling Point:401.1°Cat760mmHg
PKA:-0.95±0.40(Predicted)
Flash Point:196.4°C
PSA：80.29000
Density:1.41g/cm³
LogP:1.87150
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:289.10625597
Heavy Atom Count:21
Complexity:479

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=CC=CC=C2C(=C(C1=O)[N+](=O)[O-])N3CCOCC3

Technology Process of 1-methyl-4-(morpholin-4-yl)-3-nitroquinolin-2(1H)-one

There total 3 articles about 1-methyl-4-(morpholin-4-yl)-3-nitroquinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 110-91-8,99108-56-2
morpholine

: 79966-13-5
4-chloro-1-methyl-3-nitro-2-(1H)quinolinone

: 141945-55-3
1-methyl-(4-morpholinyl)-3-nitro-2(1H)-quinolone

Guidance literature:: In various solvent(s); Ambient temperature;

Reference yield:

: 1677-46-9
4-hydroxy-1-methyl-2(1H)-quinolone

: 141945-55-3
1-methyl-(4-morpholinyl)-3-nitro-2(1H)-quinolone

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / conc. HNO₃, NaNO₂ / acetic acid / 0.5 h

2: 92 percent / triethylamine, phosphoryl chloride / 1 h / Heating

3: 96 percent / various solvent(s) / Ambient temperature

With nitric acid; triethylamine; sodium nitrite; trichlorophosphate; In acetic acid;

Reference yield:

: 36949-55-0
4-hydroxy-1-methyl-3-nitro-2-(1H)quinolinone

: 141945-55-3
1-methyl-(4-morpholinyl)-3-nitro-2(1H)-quinolone

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / triethylamine, phosphoryl chloride / 1 h / Heating

2: 96 percent / various solvent(s) / Ambient temperature

With triethylamine; trichlorophosphate; In various solvent(s);