Piperazine,1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-

Base Information

Chemical Name:Piperazine,1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-
CAS No.:23048-89-7
Molecular Formula:C18H19 Cl N2 S
Molecular Weight:330.881
Hs Code.:

Synonyms:Dibenzo[b,f]thiepin,piperazine deriv.; 8-Chloro-10,11-dihydro-10-piperazinodibenzo[b,f]thiepin;8-Chloro-10-piperazino-10,11-dihydrodibenzo[b,f]thiepin; Dibenzo[b,f]thiepin,8-chloro-10,11-dihydro-10-(1-piperazinyl)-; Noroctoclothepine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Piperazine,1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

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Technology Process of Piperazine,1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-

There total 1 articles about Piperazine,1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13459-62-6
2-[2-(4-chlorophenyl)sulfanylphenyl]acetic acid

: 23048-89-7
1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine

Guidance literature:: Multi-step reaction with 4 steps

1: phosphorus pentoxide / 4 h / 150 °C

2: titanium(IV) isopropylate / toluene / 40 h / Inert atmosphere; Reflux

3: sodium tetrahydroborate / acetic acid / 20 °C / Inert atmosphere

4: titanium(IV) isopropylate; trifluoroacetic acid / dichloromethane / 4 h / 20 °C / Inert atmosphere

With titanium(IV) isopropylate; sodium tetrahydroborate; phosphorus pentoxide; trifluoroacetic acid; In dichloromethane; acetic acid; toluene;
DOI:10.1016/j.ejmech.2016.04.058

Reference yield: 19.0%

: 15175-04-9
2-chloroethyl decanoate

: 23048-89-7
1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine

: 41931-83-3
2-chloro-11-<4-(2-decanoyloxyethyl)piperazino>-10,11-dihydrodibenzothiepin

Guidance literature:: With triethylamine; In toluene; for 30h; Heating;

Reference yield:

: 23048-89-7
1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine

: 86490-08-6
2-chloro-11-<4-(2-mandeloyloxyethyl)piperazino>-10,11-dihydrodibenzothiepin

Guidance literature:: Multi-step reaction with 4 steps

1: 19 percent / Et₃N / toluene / 30 h / Heating

2: Na / ethanol / 4 h / Heating

3: 79 percent / SOCl₂ / pyridine; benzene / 1.)10 deg C 2.)r.t., 2 h

4: 100 percent / propan-2-ol / 7 h / Heating

With thionyl chloride; sodium; triethylamine; In pyridine; ethanol; isopropyl alcohol; toluene; benzene;