H-D-Ala-phe-OH

Base Information

Chemical Name:H-D-Ala-phe-OH
CAS No.:3061-95-8
Molecular Formula:C12H16 N2 O3
Molecular Weight:236.27
Hs Code.:
DSSTox Substance ID:DTXSID901313025
Nikkaji Number:J253.837G
ChEMBL ID:CHEMBL78953
Mol file:3061-95-8.mol

Synonyms:H-D-ALA-PHE-OH;3061-95-8;D-Alanyl-L-phenylalanine;CHEMBL78953;(S)-2-((R)-2-Aminopropanamido)-3-phenylpropanoic acid;D-Ala-Phe-OH;(2S)-2-[(2R)-2-AMINOPROPANAMIDO]-3-PHENYLPROPANOIC ACID;DTXSID901313025;BDBM50406920;MFCD00066030;AKOS006000135;CS-0208837

Suppliers and Price of H-D-Ala-phe-OH

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
H-D-Ala-phe-oh
250mg
$ 140.00

TRC
H-D-Ala-phe-oh
100mg
$ 75.00

Crysdot
(S)-2-((R)-2-Aminopropanamido)-3-phenylpropanoicacid 97%
5g
$ 389.00

Crysdot
(S)-2-((R)-2-Aminopropanamido)-3-phenylpropanoicacid 97%
25g
$ 966.00

Crysdot
(S)-2-((R)-2-Aminopropanamido)-3-phenylpropanoicacid 97%
10g
$ 584.00

Biosynth Carbosynth
D-Ala-Phe-OH
5 g
$ 460.50

Biosynth Carbosynth
D-Ala-Phe-OH
10 g
$ 736.70

Biosynth Carbosynth
D-Ala-Phe-OH
500 mg
$ 75.00

Biosynth Carbosynth
D-Ala-Phe-OH
2 g
$ 297.60

Biosynth Carbosynth
D-Ala-Phe-OH
1 g
$ 186.00

Total 17 raw suppliers

Chemical Property of H-D-Ala-phe-OH

Chemical Property:

Boiling Point:487.6°Cat760mmHg
Flash Point:248.7°C
PSA：92.42000
Density:1.222g/cm³
LogP:1.23690
Storage Temp.:-15°C
XLogP3:-2.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:236.11609238
Heavy Atom Count:17
Complexity:275

Purity/Quality:

97% ^*data from raw suppliers

H-D-Ala-phe-oh ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)NC(CC1=CC=CC=C1)C(=O)O)N
Isomeric SMILES:C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)N

Technology Process of H-D-Ala-phe-OH

There total 7 articles about H-D-Ala-phe-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 94883-19-9
D-(N-tert-butoxycarbonylalanyl)-L-phenylalanine

: 3061-95-8
D-Ala-Phe-OH

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1016/0223-5234(92)90113-F

Reference yield:

: 100431-46-7
N-<(S)-2-(aminocarbonyl)-1-oxopropyl>-L-phenyl alanine

: 3061-95-8
D-Ala-Phe-OH

Guidance literature:: With bis-(trifluoroacetoxy)-iodo-benzene; In water; acetonitrile; for 3h;
DOI:10.1021/jm00155a027

Reference yield:

: 16874-17-2
L-phenylalanine tert-butyl ester

: 3061-95-8
D-Ala-Phe-OH

Guidance literature:: Multi-step reaction with 5 steps

1: 97 percent / triethylamine, 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide / CHCl₃; tetrahydrofuran / Ambient temperature

2: 80 percent / 1N aq. NaOH / ethanol / 2 h / Ambient temperature

3: 82 percent / N-hydroxysuccinimide, N,N'-dicyclohexylcarbodiimide, NH₃ / tetrahydrofuran / Ambient temperature

4: 46 percent / TFA / CH₂Cl₂ / 3 h / 0 - 20 °C

5: benzene / acetonitrile; H₂O / 3 h

With sodium hydroxide; 1-hydroxy-pyrrolidine-2,5-dione; bis-(trifluoroacetoxy)-iodo-benzene; ammonia; benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; In tetrahydrofuran; ethanol; dichloromethane; chloroform; water; acetonitrile;
DOI:10.1021/jm00155a027