4-Methoxy-2-methylbenzaldehyde

Base Information

• Chemical Name: 4-Methoxy-2-methylbenzaldehyde
• CAS No.: 52289-54-0
• Molecular Formula: C9H10O2
• Molecular Weight: 150.177
• Hs Code.: 29124900
• NSC Number: 137775
• DSSTox Substance ID: DTXSID30966665
• Nikkaji Number: J759.686C
• Wikidata: Q72490307
• Mol file: 52289-54-0.mol

Synonyms:4-Methoxy-2-methylbenzaldehyde;52289-54-0;2-Methyl-4-methoxybenzaldehyde;4-Methoxy-2-Methyl-Benzaldehyde;MFCD02261771;Benzaldehyde, 4-methoxy-2-methyl-;NSC137775;2-Methyl-anisaldehyde;4-methoxy-2-methylbenzaldehyd;SCHEMBL135243;3-(Furane-2-amido)benzoic acid;DTXSID30966665;WICYVKGMEJSDAO-UHFFFAOYSA-N;BBL100322;STL553953;4-Methoxy-2-methylbenzaldehyde, 95%;AKOS000108196;CS-W007786;DS-0890;NSC-137775;SY017673;AM20060654;BB 0245728;FT-0600830;EN300-98075;A829012;J-509979;Z385370020;4-methoxy-2-methyl-benzaldehyde

Chemical Property of 4-Methoxy-2-methylbenzaldehyde

Chemical Property:

• Vapor Pressure: 0.00987mmHg at 25°C
• Refractive Index: n20/D 1.571(lit.)
• Boiling Point: 264.1 °C at 760 mmHg
• Flash Point: 118.9 °C
• PSA: 26.30000
• Density: 1.062 g/cm³
• LogP: 1.81610
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 150.068079557
• Heavy Atom Count: 11
• Complexity: 134

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Methoxy-2-methylbenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1)OC)C=O

Technology Process of 4-Methoxy-2-methylbenzaldehyde

There total 28 articles about 4-Methoxy-2-methylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,4-dimethylanisole (4685-47-6) → 4-methoxysalicylaldehyde (52289-54-0)

Guidance literature:

With dipotassium peroxodisulfate; copper(ll) sulfate pentahydrate; In water; acetonitrile; at 90 ℃; for 0.5h;

Reference yield: 93.0%

dicyanozinc (557-21-1) + 1-methoxy-3-methyl-benzene (100-84-5) → 4-methoxysalicylaldehyde (52289-54-0)

Guidance literature:

dicyanozinc; 1-methoxy-3-methyl-benzene; With hydrogenchloride; In 1,1,2,2-tetrachloroethane; at 17 ℃;

With aluminium trichloride; In 1,1,2,2-tetrachloroethane; at 55 ℃; for 3h;

DOI:10.1021/jm020536q

Reference yield: 93.0%

(4-methoxy-2-methylphenyl)methanol (52289-55-1) → 4-methoxysalicylaldehyde (52289-54-0)

Guidance literature:

With Florisil; Celite; pyridinium chlorochromate; In dichloromethane; for 1.3h; Ambient temperature;

DOI:10.1016/S0040-4020(01)89106-7

upstream raw materials:

4-hydroxy-2-methyl-benzaldehyde

sodium methylate

N,N-dimethyl-formamide

1-methoxy-3-methyl-benzene

Downstream raw materials:

2-Trimethylsilyl-1-(4-methoxy-2-methylphenyl)prop-2-en-1-ol

C₁₁H₁₆O₂

ethyl (E)-3-(4-methoxy-2-methylphenyl)-2-propenoate

2-(2,2-dibromovinyl)-5-methoxyphenol

Refernces

• 1、 Li, Xue,Bai, Fang,Liu, Chaogan,Ma, Xiaowei,Gu, Chengzhi,Dai, Bin. "Selective Electrochemical Oxygenation of Alkylarenes to Carbonyls". supporting information. p. 7445 - 7449. Retrieved 2021/10/02.
• 2、 Dickschat, Jeroen S.,Wang, Tao,Stadler, Marc. "Volatiles from the xylarialean fungus Hypoxylon invadens". . p. 734 - 746. Retrieved 2018/04/16.