1-{3-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}-3-(4-nitrophenyl)prop-2-en-1-one

Base Information

Chemical Name:1-{3-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}-3-(4-nitrophenyl)prop-2-en-1-one
CAS No.:5994-97-8
Molecular Formula:C₂₈H₃₂N₂Si₂
Molecular Weight:452.746
Hs Code.:
DSSTox Substance ID:DTXSID60410303

Synonyms:5994-97-8;DTXSID60410303;1-{3-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}-3-(4-nitrophenyl)prop-2-en-1-one

Suppliers and Price of 1-{3-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}-3-(4-nitrophenyl)prop-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1-{3-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}-3-(4-nitrophenyl)prop-2-en-1-one

Chemical Property:

Vapor Pressure:5.07E-17mmHg at 25°C
Boiling Point:654.8°Cat760mmHg
Flash Point:349.8°C
Density:1.37g/cm³
XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:438.1094828
Heavy Atom Count:31
Complexity:656

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(CN(C1)C(=O)C=CC2=CC=C(C=C2)[N+](=O)[O-])C3=NC(=NO3)C4=CC=C(C=C4)Cl

Technology Process of 1-{3-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}-3-(4-nitrophenyl)prop-2-en-1-one

There total 3 articles about 1-{3-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}-3-(4-nitrophenyl)prop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: C₁₂H₁₀N₂^(1-)*C₄H₁₀LiO⁽¹⁺⁾

: 768-33-2
phenyldimethylsilyl chloride

: 5994-97-8
1,2-bis(dimethyl(phenyl)silyl)-1,2-diphenylhydrazine

Guidance literature:: In tetrahydrofuran; Schlenk technique;
DOI:10.1021/acs.orglett.5b02860

Reference yield:

: 1227476-15-4
Azobenzene

: 5994-97-8
1,2-bis(dimethyl(phenyl)silyl)-1,2-diphenylhydrazine

Guidance literature:: Multi-step reaction with 2 steps

1: lithium dicyclohexylamide / Schlenk technique

2: tetrahydrofuran / Schlenk technique

With lithium dicyclohexylamide; In tetrahydrofuran;
DOI:10.1021/acs.orglett.5b02860