Bis[1-(thiophen-2-YL)ethylidene]hydrazine

Base Information

• Chemical Name: Bis[1-(thiophen-2-YL)ethylidene]hydrazine
• CAS No.: 24523-54-4
• Molecular Formula: C12H12N2S2
• Molecular Weight: 248.3671
• DSSTox Substance ID: DTXSID70947413
• Mol file: 24523-54-4.mol

Synonyms:CBDivE_012720;DTXSID70947413;HMS2816A18;BIS[1-(THIOPHEN-2-YL)ETHYLIDENE]HYDRAZINE

Chemical Property of Bis[1-(thiophen-2-YL)ethylidene]hydrazine

Chemical Property:

• Vapor Pressure: 0.000148mmHg at 25°C
• Boiling Point: 342.6°C at 760 mmHg
• Flash Point: 161°C
• Density: 1.2g/cm³
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 248.04419074
• Heavy Atom Count: 16
• Complexity: 269

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NN=C(C)C1=CC=CS1)C2=CC=CS2

Technology Process of Bis[1-(thiophen-2-YL)ethylidene]hydrazine

There total 3 articles about Bis[1-(thiophen-2-YL)ethylidene]hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-methyl-N'-(1-(thiophen-2-yl)ethylidene)benzenesulfonohydrazide → 1,2-bis(1-(thiophen-2-yl)ethylidene)hydrazine (24523-54-4)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; nitromethane; at 110 ℃; for 10h; Schlenk technique;

DOI:10.1016/j.tet.2013.03.055

Reference yield: 86.0%

2-Acetylthiophene (88-15-3,97511-16-5) → 1,2-bis(1-(thiophen-2-yl)ethylidene)hydrazine (24523-54-4)

Guidance literature:

With hydrazine hydrate; acetic acid; for 20h; Heating;

DOI:10.1139/V02-169

Reference yield:

→ 1,2-bis(1-(thiophen-2-yl)ethylidene)hydrazine (24523-54-4)

Guidance literature:

aus 2-Acetylthiophen, Hydrazinhydrat;

DOI:10.1246/bcsj.44.505

upstream raw materials:

2-Acetylthiophene

Downstream raw materials:

7-methyl-4,5-diphenylthieno[2,3-c]pyridine