((4-(4-amidinophenoxy)butanoyl)aspartyl)valine

Base Information

Chemical Name:((4-(4-amidinophenoxy)butanoyl)aspartyl)valine
CAS No.:147865-49-4
Molecular Formula:C₂₀H₂₈N₄O₇
Molecular Weight:436.465
Hs Code.:
Mol file:147865-49-4.mol

Synonyms:L-Valine,N-[N-[4-[4-(aminoiminomethyl)phenoxy]-1-oxobutyl]-L-a-aspartyl]-; FK 633; FR 144633

Suppliers and Price of ((4-(4-amidinophenoxy)butanoyl)aspartyl)valine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of ((4-(4-amidinophenoxy)butanoyl)aspartyl)valine

Chemical Property:

PSA：198.88000
Density:1.37g/cm³
LogP:2.79520

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ((4-(4-amidinophenoxy)butanoyl)aspartyl)valine

There total 4 articles about ((4-(4-amidinophenoxy)butanoyl)aspartyl)valine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (S)-2-{(S)-3-Benzyloxycarbonyl-2-[4-(4-carbamimidoyl-phenoxy)-butyrylamino]-propionylamino}-3-methyl-butyric acid benzyl ester

: 147865-49-4
dryofragin

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; water; for 4.5h; Ambient temperature;
DOI:10.1016/S0960-894X(96)00246-6

Reference yield:

: 147866-93-1
4-[4-(Benzyloxycarbonylamino-imino-methyl)-phenoxy]-butyric acid

: 147865-49-4
dryofragin

Guidance literature:: Multi-step reaction with 2 steps

1: 95.2 percent / HOBt, EDC / dimethylformamide / 2 h / Ambient temperature

2: H₂, HCl / Pd/C / tetrahydrofuran; H₂O / 4.5 h / Ambient temperature

With hydrogenchloride; hydrogen; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; palladium on activated charcoal; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(96)00246-6

Reference yield:

: L-(α-O-benzylaspartyl)-L-O-benzylvaline hydrochloride

: 147865-49-4
dryofragin

Guidance literature:: Multi-step reaction with 2 steps

1: 95.2 percent / HOBt, EDC / dimethylformamide / 2 h / Ambient temperature

2: H₂, HCl / Pd/C / tetrahydrofuran; H₂O / 4.5 h / Ambient temperature

With hydrogenchloride; hydrogen; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; palladium on activated charcoal; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(96)00246-6