2-Chloro-3,4-dihydroxy-5-nitrobenzaldehyde

Base Information

Chemical Name:2-Chloro-3,4-dihydroxy-5-nitrobenzaldehyde
CAS No.:125629-21-2
Molecular Formula:C₇H₄ClNO₅
Molecular Weight:217.565
Hs Code.:
DSSTox Substance ID:DTXSID50154825
Wikidata:Q83022175
Mol file:125629-21-2.mol

Synonyms:2-Chloro-3,4-dihydroxy-5-nitrobenzaldehyde;Benzaldehyde, 2-chloro-3,4-dihydroxy-5-nitro-;125629-21-2;C7-H4-Cl-N-O5;SCHEMBL7368834;DTXSID50154825;CSLHJKBTWPZQQO-UHFFFAOYSA-N;LS-24953

Suppliers and Price of 2-Chloro-3,4-dihydroxy-5-nitrobenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-Chloro-3,4-dihydroxy-5-nitrobenzaldehyde

Chemical Property:

Vapor Pressure:0.000472mmHg at 25°C
Boiling Point:304.9°Cat760mmHg
Flash Point:138.2°C
Density:1.786g/cm³
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:216.9777999
Heavy Atom Count:14
Complexity:243

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=C(C(=C1[N+](=O)[O-])O)O)Cl)C=O

Technology Process of 2-Chloro-3,4-dihydroxy-5-nitrobenzaldehyde

There total 4 articles about 2-Chloro-3,4-dihydroxy-5-nitrobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.3%

: 125629-47-2
2-chloro-3-hydroxy-4-methoxy-5-nitrobenzaldehyde

: 125629-21-2
2-chloro-3,4-dihydroxy-5-nitrobenzaldehyde

Guidance literature:: With boron tribromide; In dichloromethane; for 18h; Ambient temperature;
DOI:10.1002/hlca.19890720511

Reference yield:

: 37687-57-3
2-chloro-3-hydroxy-4-methoxybenzaldehyde

: 125629-21-2
2-chloro-3,4-dihydroxy-5-nitrobenzaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: 84.6 percent / pyridine / 8 h / 80 °C

2: 72.2 percent / 96percent HNO₃ / 4 h / -10 °C

3: 95.6 percent / 1 N NaOH/H₂₀ / methanol / 2 h / Ambient temperature

4: 89.3 percent / BBr₃ / CH₂Cl₂ / 18 h / Ambient temperature

With sodium hydroxide; water; nitric acid; boron tribromide; In pyridine; methanol; dichloromethane;
DOI:10.1002/hlca.19890720511

Reference yield:

: 125629-45-0
2-chloro-3-acetyloxy-4-methoxybenzaldehyde

: 125629-21-2
2-chloro-3,4-dihydroxy-5-nitrobenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 72.2 percent / 96percent HNO₃ / 4 h / -10 °C

2: 95.6 percent / 1 N NaOH/H₂₀ / methanol / 2 h / Ambient temperature

3: 89.3 percent / BBr₃ / CH₂Cl₂ / 18 h / Ambient temperature

With sodium hydroxide; water; nitric acid; boron tribromide; In methanol; dichloromethane;
DOI:10.1002/hlca.19890720511