Ethyl 1-(p-methylbenzyl)cyclopropanecarboxylate

Base Information

• Chemical Name: Ethyl 1-(p-methylbenzyl)cyclopropanecarboxylate
• CAS No.: 1621-32-5
• Molecular Formula: C14H18 O2
• Molecular Weight: 218.296
• Hs Code.: 2916399090
• European Community (EC) Number: 216-593-6
• DSSTox Substance ID: DTXSID10167310
• Nikkaji Number: J195.247A
• Wikidata: Q83036659
• Mol file: 1621-32-5.mol

Synonyms:Ethyl 1-(p-methylbenzyl)cyclopropanecarboxylate;1621-32-5;ethyl 1-[(4-methylphenyl)methyl]cyclopropane-1-carboxylate;EINECS 216-593-6;DTXSID10167310;1-[(4-Methylphenyl)methyl]cyclopropanecarboxylic acid ethyl ester;Cyclopropanecarboxylic acid, 1-((4-methylphenyl)methyl)-, ethyl ester

Chemical Property of Ethyl 1-(p-methylbenzyl)cyclopropanecarboxylate

Chemical Property:

• Vapor Pressure: 0.00166mmHg at 25°C
• Boiling Point: 294.1°Cat760mmHg
• Flash Point: 124.1°C
• PSA: 26.30000
• Density: 1.089g/cm³
• LogP: 2.88080
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 218.130679813
• Heavy Atom Count: 16
• Complexity: 248

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1(CC1)CC2=CC=C(C=C2)C

Technology Process of Ethyl 1-(p-methylbenzyl)cyclopropanecarboxylate

There total 2 articles about Ethyl 1-(p-methylbenzyl)cyclopropanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3,3-Bis-ethoxycarbonyl-4-p-tolyl-butyl)-trimethyl-ammonium; iodide → ethyl 1-(p-methylbenzyl)cyclopropanecarboxylate (1621-32-5)

Guidance literature:

Multistep reaction; (i) ion-exchange resin - form>, EtOH, (ii) (heating);

DOI:10.1021/jm00299a007

Reference yield:

→ ethyl 1-(p-methylbenzyl)cyclopropanecarboxylate (1621-32-5)

Guidance literature:

p-Tolylaldehyd, Butyrolacton, NaOMe;

Reference yield:

ethyl 1-(p-methylbenzyl)cyclopropanecarboxylate (1621-32-5) → 1-(p-methylbenzyl)cyclopropanecarboxylic acid (1804-28-0)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/jm00299a007

Downstream raw materials:

1-(p-methylbenzyl)cyclopropanecarboxylic acid

1-[(p-tolyl)methyl]cyclopropanecarbonyl chloride

1-(4-Methyl-benzyl)-cyclopropylamine