3β,16β-Dihydroxy-6-oxo-24-nor-5α-cholan-23-oic acid δ-lactone

Base Information

Chemical Name:3β,16β-Dihydroxy-6-oxo-24-nor-5α-cholan-23-oic acid δ-lactone
CAS No.:14594-22-0
Molecular Formula:C₂₃H₃₄O₄
Molecular Weight:374.521
Hs Code.:
Mol file:14594-22-0.mol

Synonyms:24-Nor-5a-cholan-23-oic acid, 3b,16b-dihydroxy-6-oxo-, d-lactone (8CI); Chiogralactone (7CI);Naphth[2',1':4,5]indeno[2,1-b]pyran, 24-norcholan-23-oic acid deriv.;Shiogralactone

Suppliers and Price of 3β,16β-Dihydroxy-6-oxo-24-nor-5α-cholan-23-oic acid δ-lactone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 3β,16β-Dihydroxy-6-oxo-24-nor-5α-cholan-23-oic acid δ-lactone

Chemical Property:

PSA：63.60000
LogP:3.74670

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3β,16β-Dihydroxy-6-oxo-24-nor-5α-cholan-23-oic acid δ-lactone

There total 6 articles about 3β,16β-Dihydroxy-6-oxo-24-nor-5α-cholan-23-oic acid δ-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 58348-04-2,75023-90-4,123484-94-6
Acetic acid (2S,10aR)-4a,6a,7-trimethyl-9-oxo-1,2,3,4,4a,4b,5,6,6a,8,9,10a,11,11a,11b,12-hexadecahydro-10-oxa-indeno[2,1-a]phenanthren-2-yl ester

: 14594-22-0
chiogralactone

Guidance literature:: Multi-step reaction with 6 steps

1: H₂ / PtO₂ / acetic acid

2: 570 mg / aq. HCl / CHCl₃; H₂O / 50 h / 20 °C

3: 1) toluensulfonyl chloride, pyridine, 2.) KHCO₃, water / 1.) 4 deg C, 48h, 2.) acetone, reflux 6h

4: 75 mg / CrO₃*pyridine complex / 1.) 0 deg C, 2h, 2.) 20 deg C, 18h

5: 37 mg / conc. H₂SO₄ / 18 h / 20 °C

6: 25 mg

With pyridine; hydrogenchloride; chromium trioxide-pyridine complex; sulfuric acid; water; hydrogen; potassium hydrogencarbonate; p-toluenesulfonyl chloride; platinum(IV) oxide; In chloroform; water; acetic acid;
DOI:10.1007/BF00580553

Reference yield:

: (2S,7R,10aR)-2-Hydroxy-4a,6a,7-trimethyl-2,3,4,4a,4b,5,6,6a,6b,7,8,10a,11,11a,11b,12-hexadecahydro-1H-10-oxa-indeno[2,1-a]phenanthren-9-one

: 14594-22-0
chiogralactone

Guidance literature:: Multi-step reaction with 5 steps

1: 570 mg / aq. HCl / CHCl₃; H₂O / 50 h / 20 °C

2: 1) toluensulfonyl chloride, pyridine, 2.) KHCO₃, water / 1.) 4 deg C, 48h, 2.) acetone, reflux 6h

3: 75 mg / CrO₃*pyridine complex / 1.) 0 deg C, 2h, 2.) 20 deg C, 18h

4: 37 mg / conc. H₂SO₄ / 18 h / 20 °C

5: 25 mg

With pyridine; hydrogenchloride; chromium trioxide-pyridine complex; sulfuric acid; water; potassium hydrogencarbonate; p-toluenesulfonyl chloride; In chloroform; water;
DOI:10.1007/BF00580553

Reference yield:

: 87302-04-3
C₂₃H₃₄O₃

: 14594-22-0
chiogralactone

Guidance literature:: Multi-step reaction with 3 steps

1: 75 mg / CrO₃*pyridine complex / 1.) 0 deg C, 2h, 2.) 20 deg C, 18h

2: 37 mg / conc. H₂SO₄ / 18 h / 20 °C

3: 25 mg

With chromium trioxide-pyridine complex; sulfuric acid;
DOI:10.1007/BF00580553