Technology Process of 3-Hydroxy-5-methylhexanoic acid
There total 13 articles about 3-Hydroxy-5-methylhexanoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
samarium diiodide;
In
tetrahydrofuran;
at 25 ℃;
for 3.5h;
DOI:10.1021/jo060118j
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium tetrahydroborate / methanol / 0.33 h / 0 °C
2: lithium hydroxide / tetrahydrofuran; water / 2.5 h / Reflux
With
sodium tetrahydroborate; lithium hydroxide;
In
tetrahydrofuran; methanol; water;
DOI:10.1002/cbic.201402670
- Guidance literature:
-
tert-butyl 3-hydroxy-5-methylhexanoate;
With
methanol; potassium hydroxide;
at 20 - 30 ℃;
With
hydrogenchloride;
In
water;
pH=2.0;
