N-(4-hydroxyphenyl)furan-2-carboxamide

Base Information

• Chemical Name: N-(4-hydroxyphenyl)furan-2-carboxamide
• CAS No.: 4104-33-0
• Molecular Formula: C₁₁H₉NO₃
• Molecular Weight: 203.197
• Hs Code.: 2932190090
• DSSTox Substance ID: DTXSID90353678
• Nikkaji Number: J1.612.274B
• Wikidata: Q82131390
• Mol file: 4104-33-0.mol

Synonyms:N-(4-hydroxyphenyl)furan-2-carboxamide;4104-33-0;Furan-2-carboxylic acid (4-hydroxy-phenyl)-amide;N-(4-hydroxyphenyl)-2-furamide;Cambridge id 5471987;Oprea1_431396;SCHEMBL6637453;DTXSID90353678;DGVKXCATWIGAIF-UHFFFAOYSA-N;STK032597;AKOS000603489;CS-0220427;EN300-06629;AB00086167-01;Furan-2-carboxylic acid(4-hydroxy-phenyl)-amide;AG-690/12868646;SR-01000481288;SR-01000481288-1;Z56943555;F1153-0320;furan-2-carboxylic acid (4-hydroxy-phenyl)-amide, AldrichCPR

Chemical Property of N-(4-hydroxyphenyl)furan-2-carboxamide

Chemical Property:

• Vapor Pressure: 0.00292mmHg at 25°C
• Boiling Point: 276°Cat760mmHg
• Flash Point: 120.7°C
• PSA: 65.96000
• Density: 1.358g/cm³
• LogP: 2.62150
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 203.058243149
• Heavy Atom Count: 15
• Complexity: 224

Purity/Quality:

97% ^*data from raw suppliers

N-(4-hydroxyphenyl)furan-2-carboxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=C1)C(=O)NC2=CC=C(C=C2)O

Technology Process of N-(4-hydroxyphenyl)furan-2-carboxamide

There total 2 articles about N-(4-hydroxyphenyl)furan-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

2-furancarbonyl chloride (527-69-5) + 4-amino-phenol (123-30-8) → N-(4-hydroxyphenyl)furan-2-carboxamide (4104-33-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In water; at 0 ℃; Micellar solution;

DOI:10.1021/acs.oprd.0c00303

Reference yield:

→ N-(4-hydroxyphenyl)furan-2-carboxamide (4104-33-0)

Guidance literature:

O,N-Dipyromucyl-p-aminophenol, 5percentig. ethanol. KOH;

upstream raw materials:

2-furancarbonyl chloride

4-amino-phenol