5-Acetyl-2-amino-4-hydroxybenzonitrile

Base Information

Chemical Name:5-Acetyl-2-amino-4-hydroxybenzonitrile
CAS No.:71408-03-2
Molecular Formula:C₉H₈N₂O₂
Molecular Weight:176.175
Hs Code.:
DSSTox Substance ID:DTXSID30383035
Wikidata:Q82174588

Synonyms:5-acetyl-2-amino-4-hydroxybenzonitrile;71408-03-2;5-acetyl-2-amino-4-hydroxy-benzonitrile;SCHEMBL9853904;DTXSID30383035;VAXODCHUNJTZSO-UHFFFAOYSA-N;MFCD05665891;STK785140;AKOS005620791;Benzonitrile, 5-acetyl-2-amino-4-hydroxy-;CS-0319526

Suppliers and Price of 5-Acetyl-2-amino-4-hydroxybenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 5-Acetyl-2-amino-4-hydroxybenzonitrile

Chemical Property:

Vapor Pressure:9.9E-08mmHg at 25°C
Boiling Point:422.3°Cat760mmHg
Flash Point:209.2°C
PSA：87.11000
Density:1.35g/cm³
LogP:1.62988
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:176.058577502
Heavy Atom Count:13
Complexity:256

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C(C=C(C(=C1)C#N)N)O

Technology Process of 5-Acetyl-2-amino-4-hydroxybenzonitrile

There total 2 articles about 5-Acetyl-2-amino-4-hydroxybenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71043-35-1
3-methoxymethylenepentane-2,4-dione

: 109-77-3
malononitrile

: 71408-03-2
5-Acetyl-2-amino-4-hydroxybenzonitril

Guidance literature:: With magnesium methanolate; In methanol; Ambient temperature;

Reference yield:

: 33884-41-2
ethoxylideneacetylacetone

: 109-77-3
malononitrile

: 71408-03-2
5-Acetyl-2-amino-4-hydroxybenzonitril

Guidance literature:: With hydrogenchloride; sodium ethanolate; Yield given. Multistep reaction; 1. EtOH, 15 min, room temperature; 2. EtOH, 1.5 h, reflux; 3. H₂O;