3,4-Dihydro-2,5-dimethyl-2H-pyran-2-methanol

Base Information

• Chemical Name: 3,4-Dihydro-2,5-dimethyl-2H-pyran-2-methanol
• CAS No.: 54004-34-1
• Molecular Formula: C8H14 O2
• Molecular Weight: 142.198
• Hs Code.: 2932999099
• European Community (EC) Number: 258-912-1
• NSC Number: 82306
• DSSTox Substance ID: DTXSID70970660
• Nikkaji Number: J110.626K
• Mol file: 54004-34-1.mol

Synonyms:3,4-Dihydro-2,5-dimethyl-2H-pyran-2-methanol;54004-34-1;(2,5-dimethyl-3,4-dihydropyran-2-yl)methanol;EINECS 258-912-1;2H-Pyran-2-methanol, 3,4-dihydro-2,5-dimethyl-;2,5-Dimethyl-3,4-dihydro-2H-pyran-2-carbinol;NSC82306;(2,5-Dimethyl-3,4-dihydro-2H-pyran-2-yl)methanol;2,5-DIMETHYL-2,3-DIHYDRO-4H-PYRAN-2-METHANOL;SCHEMBL10874861;DTXSID70970660;2,4-dihydro-2H-pyran-2-carbinol;NSC 82306;NSC-82306;AKOS024332383;2H-Pyran-2-methanol,4-dihydro-2,5-dimethyl-;(2,5-Dimethyl-3,4-dihydro-2H-pyran-2-yl)methanol #

Chemical Property of 3,4-Dihydro-2,5-dimethyl-2H-pyran-2-methanol

Chemical Property:

• Vapor Pressure: 0.0294mmHg at 25°C
• Boiling Point: 216.9°Cat760mmHg
• Flash Point: 84.2°C
• PSA: 29.46000
• Density: 0.975g/cm³
• LogP: 1.45160
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 142.099379685
• Heavy Atom Count: 10
• Complexity: 151

Purity/Quality:

99% ^*data from raw suppliers

2,5-DIMETHYL-2,3-DIHYDRO-4H-PYRAN-2-METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=COC(CC1)(C)CO

Technology Process of 3,4-Dihydro-2,5-dimethyl-2H-pyran-2-methanol

There total 6 articles about 3,4-Dihydro-2,5-dimethyl-2H-pyran-2-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-methylpropenal (78-85-3,25120-30-3) → 2,5-dimethyl-3,4-dihydro-2H-pyran-2-methanol (54004-34-1) + sodium 2,5-dimethyl-3,4-dihydro-2H-pyran-2-carboxylate (1185534-10-4)

Guidance literature:

With sodium hydroxide; water; at 40 ℃; for 0.5h;

DOI:10.1007/s10593-009-0200-3

Reference yield:

2,5-dimethyl-3,4-dihydro-2H-pyran-2-carbaldehyde (1920-21-4) → 2,5-dimethyl-3,4-dihydro-2H-pyran-2-methanol (54004-34-1)

Guidance literature:

With nickel; Hydrogenation;

Reference yield:

2,5-dimethyl-3,4-dihydro-2H-pyran-2-carbaldehyde (1920-21-4) → 2,5-dimethyl-3,4-dihydro-2H-pyran-2-methanol (54004-34-1) + 1,4-dimethyl-6,8-dioxa-bicyclo[3.2.1]octan-7-one (13434-06-5)

Guidance literature:

With sodium hydroxide; anschliessendes Ansaeuern mit wss. Salzsaeure;

DOI:10.1021/ja01160a028

upstream raw materials:

2,5-dimethyl-3,4-dihydro-2H-pyran-2-carbaldehyde

1-methyl-4-nitrosobenzene

methoxyethene

2-methylpropenal

Downstream raw materials:

3-hydroxy-2-methyl-1-propene