Technology Process of Juncunol
There total 5 articles about Juncunol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium methanethiolate;
In
N,N,N,N,N,N-hexamethylphosphoric triamide;
at 150 - 180 ℃;
for 2h;
DOI:10.1016/S0040-4039(00)78676-X
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) KCN, HCl, 2.) POCl3 / 1.) THF, H2O, 24 deg C, 18 h, 2.) pyridine, 24 deg C, 4 h
2: 87 percent / CuBr2 / methanol / Heating
3: 92 percent / diisobutylaluminium hydride / benzene / 18 h / 24 °C
4: 74 percent / n-BuLi / diethyl ether / 18 h / 24 °C
5: 73 percent / lithium thiomethoxide / hexamethylphosphoric acid triamide / 2 h / 150 - 180 °C
With
hydrogenchloride; potassium cyanide; n-butyllithium; diisobutylaluminium hydride; lithium methanethiolate; copper(ll) bromide; trichlorophosphate;
In
methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; benzene;
DOI:10.1016/S0040-4039(00)78676-X
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 74 percent / n-BuLi / diethyl ether / 18 h / 24 °C
2: 73 percent / lithium thiomethoxide / hexamethylphosphoric acid triamide / 2 h / 150 - 180 °C
With
n-butyllithium; lithium methanethiolate;
In
N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether;
DOI:10.1016/S0040-4039(00)78676-X
