2-nitrobenzyl propanoate

Base Information

• Chemical Name: 2-nitrobenzyl propanoate
• CAS No.: 132663-51-5
• Molecular Formula: C10H11NO4
• Molecular Weight: 209.1986
• Mol file: 132663-51-5.mol

Synonyms:

Chemical Property of 2-nitrobenzyl propanoate

Chemical Property:

• Vapor Pressure: 0.00149mmHg at 25°C
• Boiling Point: 295.8°Cat760mmHg
• Flash Point: 126.1°C
• Density: 1.226g/cm³

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-nitrobenzyl propanoate

There total 2 articles about 2-nitrobenzyl propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-nitrobenzyl chloride (612-23-7) + propionic acid (802294-64-0,79-09-4) → o-nitrobenzyl propionate (132663-51-5)

Guidance literature:

With triethylamine; sodium iodide; In ethyl acetate; for 20h; Heating;

DOI:10.1016/0223-5234(90)90146-T

Reference yield:

propanoate (72-03-7) + 2-nitrophenylmethyl bromide (3958-60-9) → o-nitrobenzyl propionate (132663-51-5)

Guidance literature:

With silica; tetrabutylammomium bromide; sodium butyrate; 2,4-dimethylpentan-3-one; In water; at 57 ℃; for 5h;

DOI:10.1016/j.mcat.2020.111335

upstream raw materials:

2-nitrobenzyl chloride

propionic acid

propanoate

2-nitrophenylmethyl bromide

Refernces

• 1、 Wakselman,Cerutti,Chany. "Nitrobenzyl esters as potential conjugated alkylating and differentiation promoting agents: Antitumor effect in vivo". . p. 519 - 526. Retrieved 2007/10/02.