Acetamide, N-(4-(2-oxo-2-phenylethyl)phenyl)-

Base Information

Chemical Name:Acetamide, N-(4-(2-oxo-2-phenylethyl)phenyl)-
CAS No.:30566-19-9
Molecular Formula:C₁₆H₁₅NO₂
Molecular Weight:253.301
Hs Code.:
UNII:T8VX6V48PV
DSSTox Substance ID:DTXSID80184650
Wikidata:Q83055565
Mol file:30566-19-9.mol

Synonyms:4'-Phenacylacetanilide;beta-Keto-4-acetylaminobibenzyl;4'-Acetamidodeoxybenzoin;Acetanilide, 4'-phenacyl-;30566-19-9;BRN 2942025;ACETAMIDE, N-(4-(2-OXO-2-PHENYLETHYL)PHENYL)-;Acetamide, N-[4-(2-oxo-2-phenylethyl)phenyl]-;T8VX6V48PV;SCHEMBL1627028;DTXSID80184650;Keto-4-acetylaminobibenzyl, beta-;N-[4-(2-OXO-2-PHENYLETHYL)PHENYL]ACETAMIDE

Suppliers and Price of Acetamide, N-(4-(2-oxo-2-phenylethyl)phenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetamide, N-(4-(2-oxo-2-phenylethyl)phenyl)-

Chemical Property:

Vapor Pressure:3.21E-09mmHg at 25°C
Boiling Point:475.8°Cat760mmHg
Flash Point:188°C
Density:1.179g/cm³
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:253.110278721
Heavy Atom Count:19
Complexity:313

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=C(C=C1)CC(=O)C2=CC=CC=C2

Technology Process of Acetamide, N-(4-(2-oxo-2-phenylethyl)phenyl)-

There total 6 articles about Acetamide, N-(4-(2-oxo-2-phenylethyl)phenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 31841-17-5
N-(4-(2-oxo-2-phenylacetyl)phenyl)acetamide

: 30566-19-9
N-(4-(2-oxo-2-phenylethyl)phenyl)acetamide

Guidance literature:: N-(4-(2-oxo-2-phenylacetyl)phenyl)acetamide; With sodium iodide; In dichloromethane; at 20 ℃; for 0.0833333h; Inert atmosphere; Green chemistry;

With chloro-trimethyl-silane; In dichloromethane; at 20 ℃; for 4h; regioselective reaction; Inert atmosphere; Green chemistry;
DOI:10.1021/acs.orglett.6b01491

Reference yield:

: 536-74-3
phenylacetylene

: N-(4-(2-phenylacetyl)phenyl)acetamide

: 30566-19-9
N-(4-(2-oxo-2-phenylethyl)phenyl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 30 °C / Inert atmosphere

2: triethylamine / dichloromethane / 1 h / 0 °C / Inert atmosphere; Schlenk technique

3: 1,3-di(2,6-diisopropylphenyl)-4,5-diundecylimidazolium bromide; silver tetrafluoroborate; sodium dodecyl-sulfate; water / 48 h / 50 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; silver tetrafluoroborate; 1,3-di(2,6-diisopropylphenyl)-4,5-diundecylimidazolium bromide; water; sodium dodecyl-sulfate; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1002/chem.201502542

Reference yield:

: N-(4-(2-phenylethynyl)phenyl)acetamide

: N-(4-(2-phenylacetyl)phenyl)acetamide

: 30566-19-9
N-(4-(2-oxo-2-phenylethyl)phenyl)acetamide

Guidance literature:: With silver tetrafluoroborate; 1,3-di(2,6-diisopropylphenyl)-4,5-diundecylimidazolium bromide; water; sodium dodecyl-sulfate; at 50 ℃; for 48h; Overall yield = 85 %; Overall yield = 107 mg; Inert atmosphere;
DOI:10.1002/chem.201502542