2-(P-N,N-DIMETHYLAMINOPHENYL)-1H-BENZOIMIDAZOLE

Base Information

• Chemical Name: 2-(P-N,N-DIMETHYLAMINOPHENYL)-1H-BENZOIMIDAZOLE
• CAS No.: 2562-71-2
• Molecular Formula: C15H15 N3
• Molecular Weight: 237.304
• Hs Code.: 2933290090
• Mol file: 2562-71-2.mol

Synonyms:Benzimidazole,2-[p-(dimethylamino)phenyl]- (6CI,7CI,8CI);2-(4-Dimethylaminophenyl)-1H-benzimidazole; 2-(p-Dimethylaminophenyl)benzimidazole;2-[4-(Dimethylamino)phenyl]benzimidazole;4-(1H-Benzimidazol-2-yl)-N,N-dimethylaniline; NSC 51680

Chemical Property of 2-(P-N,N-DIMETHYLAMINOPHENYL)-1H-BENZOIMIDAZOLE

Chemical Property:

• Vapor Pressure: 3.57E-08mmHg at 25°C
• Boiling Point: 446.7°Cat760mmHg
• Flash Point: 224°C
• PSA: 31.92000
• Density: 1.196g/cm³
• LogP: 3.29590

Purity/Quality:

N-[4-(1H-benzimidazol-2-yl)phenyl]-N,N-dimethylamine AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(P-N,N-DIMETHYLAMINOPHENYL)-1H-BENZOIMIDAZOLE

There total 23 articles about 2-(P-N,N-DIMETHYLAMINOPHENYL)-1H-BENZOIMIDAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,2-diamino-benzene (95-54-5) + 4-dimethylamino-benzaldehyde (100-10-7) → 2-(4-dimethylaminophenyl)-1H-benzimidazole (2562-71-2)

Guidance literature:

With hydrogenchloride; dihydrogen peroxide; In acetonitrile; at 20 ℃; for 0.666667h;

DOI:10.1055/s-2007-965878

Reference yield: 97.0%

2-iodophenylamine (615-43-0) + 4-dimethylamino-benzaldehyde (100-10-7) → 2-(4-dimethylaminophenyl)-1H-benzimidazole (2562-71-2)

Guidance literature:

With sodium azide; N,N,N,N,-tetramethylethylenediamine; copper(l) chloride; In dimethyl sulfoxide; at 120 ℃; for 12h;

DOI:10.1021/jo2019416

Reference yield: 95.0%

1,2-diamino-benzene (95-54-5) + N,N-dimethyl-4-hydroxymethylaniline (1703-46-4) → 2-(4-dimethylaminophenyl)-1H-benzimidazole (2562-71-2)

Guidance literature:

With sodium t-butanolate; In water; at 75 ℃; for 6h; Green chemistry;

DOI:10.1080/00397911.2015.1017053

upstream raw materials:

1,2-diamino-benzene

4-dimethylamino-benzaldehyde

(4-dimethylamino-benzylidene)-o-phenylenediamine

p-N,N-dimethylaminobenzoic acid

Downstream raw materials:

2-(4'-N,N-dimethylaminophenyl)-1-methylsulphanylmethyl-1H-benzimidazole

1-methyl-2-(4-N,N-dimethylaminophenyl)benzimidazole