Zafuleptine

Base Information

Chemical Name:Zafuleptine
CAS No.:59209-97-1
Molecular Formula:C₁₇H₂₆FNO₂
Molecular Weight:295.397
Hs Code.:
European Community (EC) Number:261-658-4
UNII:46CR2R0F2N,E697IIC25J,X5ZE606573
DSSTox Substance ID:DTXSID60866745
Nikkaji Number:J325.954D
Wikipedia:Zafuleptine
Wikidata:Q8064324
NCI Thesaurus Code:C66679
ChEMBL ID:CHEMBL2106479
Mol file:59209-97-1.mol

Synonyms:Zafuleptine;59209-97-1;Zafuleptine [INN];Zafuleptina [Spanish];Zafuleptina;Zafuleptinum;7-[(4-fluorophenyl)methylamino]-8-methylnonanoic acid;Zafuleptinum [Latin];Zafuleptine, (+)-;Zafuleptine, (-)-;UNII-E697IIC25J;46CR2R0F2N;E697IIC25J;EINECS 261-658-4;X5ZE606573;7-((4-Fluorobenzyl)amino)-8-methylnonanoic acid;Nonanoic acid, 7-(((4-fluorophenyl)methyl)amino)-8-methyl-, (+)-;Nonanoic acid, 7-(((4-fluorophenyl)methyl)amino)-8-methyl-, (-)-;59210-05-8;59210-06-9;7-[[(4-Fluorophenyl)methyl]amino]-8-methylnonanoic acid;7-(((4-FLUOROPHENYL)METHYL)AMINO)-8-METHYLNONANOIC ACID;ZINCACETATEDIHYDRATE;UNII-46CR2R0F2N;C17H26FNO2;SCHEMBL2110004;CHEMBL2106479;UNII-X5ZE606573;DTXSID60866745;C17-H26-F-N-O2;SB82555;7-((4-Fluorobenzyl)amino)-8-methylnonanoicacid;Q8064324;(+-)-7-((p-Fluorobenzyl)amino)-8-methylnonanoic acid;(+-)-7-[[(4-fluorophenyl)methyl]amino]-8-methylnonan-1-oic acid;(1)-7-(((4-Fluorophenyl)methyl)amino)-8-methylnonan-1-oic acid;NONANOIC ACID, 7-(((4-FLUOROPHENYL)METHYL)AMINO)-8-METHYL-;(+)-7-(((4-FLUOROPHENYL)METHYL)AMINO)-8-METHYLNONANOIC ACID;(-)-7-(((4-FLUOROPHENYL)METHYL)AMINO)-8-METHYLNONANOIC ACID;NONANOIC ACID, 7-(((4-FLUOROPHENYL)METHYL)AMINO)-8-METHYL-, (+/-)-

Suppliers and Price of Zafuleptine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of Zafuleptine

Chemical Property:

Vapor Pressure:8.11E-08mmHg at 25°C
Boiling Point:420.4°C at 760 mmHg
Flash Point:208°C
PSA：49.33000
Density:1.057g/cm³
LogP:4.36590
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:295.19475723
Heavy Atom Count:21
Complexity:289

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(CCCCCC(=O)O)NCC1=CC=C(C=C1)F
Therapeutic Function Antidepressant

Technology Process of Zafuleptine

There total 8 articles about Zafuleptine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 59209-97-1,59210-05-8,59210-06-9
7-(4-fluorobenzylamino)-8-methylnonanoic acid

Guidance literature:

Reference yield: 40.0%

: 64877-78-7,64877-82-3,64877-85-6
ethyl 7-(4-fluorobenzylamino)-8-methylnonanoate

: 59209-97-1,59210-05-8,59210-06-9
7-(4-fluorobenzylamino)-8-methylnonanoic acid

Guidance literature:: With sodium hydroxide; In ethanol; at 10 ℃; for 2h;

Reference yield:

: 459-57-4
4-fluorobenzaldehyde

: 59209-97-1,59210-05-8,59210-06-9
7-(4-fluorobenzylamino)-8-methylnonanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) zinc powder, acetic acid, 3.) sodium borohydride

2: 40 percent / aq. NaOH / ethanol / 2 h / 10 °C

With sodium hydroxide; sodium tetrahydroborate; acetic acid; zinc; In ethanol;