2-(2-Furylmethyl)cyclohexanamine

Base Information

• Chemical Name: 2-(2-Furylmethyl)cyclohexanamine
• CAS No.: 67823-66-9
• Molecular Formula: C11H18NO+
• Molecular Weight: 179.2588
• Hs Code.: 2932190090
• DSSTox Substance ID: DTXSID60406963
• Mol file: 67823-66-9.mol

Synonyms:2-(2-furylmethyl)cyclohexanamine;67823-66-9;2-(furan-2-ylmethyl)cyclohexan-1-amine;2-(Furan-2-ylmethyl)cyclohexanamine;SCHEMBL5863707;DTXSID60406963;1-(a-furfuryl)-2-aminocyclohexane;AKOS000122989;AKOS017279129;2-[(furan-2-yl)methyl]cyclohexan-1-amine;EN300-12430;F8880-8627

Chemical Property of 2-(2-Furylmethyl)cyclohexanamine

Chemical Property:

• Vapor Pressure: 0.0111mmHg at 25°C
• Boiling Point: 262.1°Cat760mmHg
• Flash Point: 112.3°C
• PSA: 39.16000
• Density: 1.023g/cm³
• LogP: 3.03990
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 179.131014166
• Heavy Atom Count: 13
• Complexity: 160

Purity/Quality:

2-(2-FURYLMETHYL)CYCLOHEXANAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCC(C(C1)CC2=CC=CO2)N
• Uses: 2-(Furan-2-ylmethyl)cyclohexan-1-amine is used in the oxidative coupling of 3,4,4a,5-tetrahydropyrido[1,2-a]benzimidazoles with some biologically active amines.

Technology Process of 2-(2-Furylmethyl)cyclohexanamine

There total 2 articles about 2-(2-Furylmethyl)cyclohexanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-2-((furan-2-yl)methylene)cyclohexanone (10496-51-2,136118-15-5) → 2-furfuryl-cyclohexylamine (67823-66-9)

Guidance literature:

With ammonia; hydrogen; nickel; at 100 ℃;

DOI:10.1007/BF02464306

Reference yield:

→ 2-furfuryl-cyclohexylamine (67823-66-9)

Guidance literature:

2-Furfuryliden-cyclohexanon/ges.methanol. NH3, H2 (Raney-Ni, 80-100grad, 3-4h, 100-120 atm.);

Reference yield: 63.0%

2-furfuryl-cyclohexylamine (67823-66-9) + 6,7-tetramethylene-1,2,3,4a,5-hexahydro-13H-benzimidazo[2,1-j]quinoline (55755-60-7) → 8-[2-(2-furylmethyl)cyclohexylimino]-1,2;4,4a-di(tetramethylene)-3,4,4a,8-tetrahydropyrido[1,2-a]benzimidazole

Guidance literature:

With manganese(IV) oxide; In acetone; at 20 ℃;

DOI:10.1134/S1070428009020195

upstream raw materials:

(E)-2-((furan-2-yl)methylene)cyclohexanone

Downstream raw materials:

1-(2'-Tetrahydrofurfuryl)-2-aminocyclohexane

3-(2-octahydroindolyl)propan-1-ol

3-(2-furan-2-ylmethyl-cyclohexylamino)-propionitrile

N¹-(2-furan-2-ylmethyl-cyclohexyl)-propane-1,3-diamine

Refernces