Chemical Property of 5,14,23-Triethyl-2,11,20,29,32-pentamethyl-4,13,22,31,37,38,39,40-octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane-3,12,21,30-tetrone
Chemical Property:
- Vapor Pressure:5.92E-34mmHg at 25°C
- Boiling Point:909.7°Cat760mmHg
- Flash Point:356°C
- PSA：142.12000
- Density:1.024g/cm3
- LogP:7.19230
- XLogP3:8.2
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:12
- Rotatable Bond Count:3
- Exact Mass:778.48672766
- Heavy Atom Count:55
- Complexity:1270
- Purity/Quality:
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>95% by HPLC *data from raw suppliers
Trinactin *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CCC1CC2CCC(O2)C(C(=O)OC(CC3CCC(O3)C(C(=O)OC(CC4CCC(O4)C(C(=O)OC(CC5CCC(O5)C(C(=O)O1)C)CC)C)CC)C)C)C
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Uses
Trinactin is a member of the macrotetrolide complex produced by a range of Streptomyces sp.. Early literature reported that trinactin is a monovalent cation ionophore with high selectivity for ammonium and potassium. Trinactin inhibits T-cell proliferation induced by IL-2, and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and interferon-γ. Trinactin has not previously been available for intensive investigation. Trinactin is a hydrophobic cyclic ester that acts as a macrotetrolide antibiotic.
