1-Hydroxy-3-(2-methylphenyl)urea

Base Information

Chemical Name:1-Hydroxy-3-(2-methylphenyl)urea
CAS No.:28788-17-2
Molecular Formula:C8H10 N2 O2
Molecular Weight:166.18
Hs Code.:
NSC Number:110669
DSSTox Substance ID:DTXSID40296642
Nikkaji Number:J1.785.823H
Wikidata:Q82037331
Mol file:28788-17-2.mol

Synonyms:28788-17-2;1-hydroxy-3-(2-methylphenyl)urea;NSC110669;DTXSID40296642;NSC-110669

Suppliers and Price of 1-Hydroxy-3-(2-methylphenyl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 1-Hydroxy-3-(2-methylphenyl)urea

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.292g/cm³
XLogP3:0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:166.074227566
Heavy Atom Count:12
Complexity:161

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1NC(=O)NO

Technology Process of 1-Hydroxy-3-(2-methylphenyl)urea

There total 3 articles about 1-Hydroxy-3-(2-methylphenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51458-00-5
N-(benzyloxy)-N'-(o-methylphenyl)urea

: 28788-17-2
N-hydroxy-N'-(o-methylphenyl)urea

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 3h;
DOI:10.1248/cpb.50.1280

Reference yield:

: 614-68-6
2-tolyl isocyanate

: 28788-17-2
N-hydroxy-N'-(o-methylphenyl)urea

Guidance literature:: With sodium hydroxide; hydroxylamine hydrochloride;
DOI:10.1021/jm00297a069

Reference yield:

: 95-53-4
o-toluidine

: 28788-17-2
N-hydroxy-N'-(o-methylphenyl)urea

Guidance literature:: Multi-step reaction with 3 steps

1: aq. Na₂CO₃ / CH₂Cl₂ / 1.5 h / 20 °C

2: 710 mg / methanol; CH₂Cl₂; H₂O / 15 h

3: 517.8 mg / H₂ / 10 percent Pd/C / methanol / 3 h / 20 °C

With hydrogen; sodium carbonate; palladium on activated charcoal; In methanol; dichloromethane; water;
DOI:10.1248/cpb.50.1280