lactose 1-phosphate

Base Information

• Chemical Name: lactose 1-phosphate
• CAS No.: 20057-11-8
• Molecular Formula: C12H23O14P
• Molecular Weight: 422.28
• Mol file: 20057-11-8.mol

Synonyms:Lact1P;Lactose 1-phosphate;

Chemical Property of lactose 1-phosphate

Chemical Property:

• Boiling Point: 811.7±75.0 °C(Predicted)
• PKA: 1.73±0.10(Predicted)
• PSA: 245.87000
• Density: 1.89±0.1 g/cm3(Predicted)
• LogP: -5.28020

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of lactose 1-phosphate

There total 3 articles about lactose 1-phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1',2',3',6',2,3,4,6-octa-O-acetyl-β-D-lactose (3616-19-1,5328-50-7,5346-90-7,6291-42-5,6920-00-9,20764-63-0,20880-60-8,20880-65-3,22352-19-8,23973-20-8,32447-69-1,34213-32-6,52554-32-2,53956-64-2,56907-29-0,56994-12-8,56994-13-9,57128-38-8,67650-36-6,68036-17-9,68036-19-1,78215-50-6,78215-51-7,79549-48-7,80446-82-8,85249-04-3,93221-83-1,93779-27-2,111407-83-1,111407-84-2,111407-85-3,120328-65-6,123809-59-6,132341-46-9,132341-47-0,132341-49-2,145307-94-4) → O4-β-D-Galactopyranosyl-O1-phosphono-β-D-glucopyranose (13168-12-2,15896-49-8,20057-11-8,52689-58-4,93221-84-2,99296-40-9,105761-60-2,105761-61-3)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen bromide; acetic acid

2: chloroform; diethyl ether; silver dihydrogenphosphate / Behandeln des Barium-Salzes des Reaktionsprodukts mit wenig Kaliummethylat in Aethanol

With silver dihydrogenphosphate; diethyl ether; chloroform; hydrogen bromide; acetic acid;

DOI:10.1021/ja01136a513

Reference yield:

2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide (4753-07-5) → O4-β-D-Galactopyranosyl-O1-phosphono-β-D-glucopyranose (13168-12-2,15896-49-8,20057-11-8,52689-58-4,93221-84-2,99296-40-9,105761-60-2,105761-61-3)

Guidance literature:

With silver dihydrogenphosphate; diethyl ether; chloroform; Behandeln des Barium-Salzes des Reaktionsprodukts mit wenig Kaliummethylat in Aethanol;

DOI:10.1021/ja01136a513

Reference yield:

2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide (4753-07-5) → O4-β-D-Galactopyranosyl-O1-phosphono-β-D-glucopyranose (13168-12-2,15896-49-8,20057-11-8,52689-58-4,93221-84-2,99296-40-9,105761-60-2,105761-61-3)

Guidance literature:

With calcium sulfate; benzene; Hydrieren des Reaktionsprodukts an Palladium in Aethanol und Behandeln des Barium-Salzes des danach isolierten Reaktionsprodukts mit Natriumaethylat in Aethanol;

upstream raw materials:

2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide

1',2',3',6',2,3,4,6-octa-O-acetyl-β-D-lactose