1-Dodecanoyl-sn-glycero-3-phosphocholine

Base Information

Chemical Name:1-Dodecanoyl-sn-glycero-3-phosphocholine
CAS No.:20559-18-6
Molecular Formula:C20H42 N O7 P
Molecular Weight:439.52
Hs Code.:2923900090
UNII:V4Z2U6E9RE
DSSTox Substance ID:DTXSID50942749
Wikidata:Q27145041
Metabolomics Workbench ID:14990
ChEMBL ID:CHEMBL566871
Mol file:20559-18-6.mol

Synonyms:20559-18-6;1-Dodecanoyl-sn-glycero-3-phosphocholine;L-alpha-Lysophosphatidylcholine, lauroyl;1-lauroyl-sn-glycero-3-phosphocholine;1-Dodecanoyllysolecithin;L-ALPHA-LYSOPHOSPHATIDYLCHOLINE,LAUROYL;V4Z2U6E9RE;1-Dodecanoyl-sn-glycerol-3-phosphorylcholine;CHEBI:74966;PC(12:0/0:0);1-Lauroyl-2-hydroxy-sn-glycero-3-phosphocholine;1-Lauroyl-L-alpha-phosphorylcholine;[(2R)-3-dodecanoyloxy-2-hydroxypropyl] 2-(trimethylazaniumyl)ethyl phosphate;alpha-L-Lysophosphatidylcholine dodecyl;Choline, hydroxide, dihydrogen phosphate, inner salt, 3-ester with 1-monolaurin, L-;Laurin, 1-mono-, 3-(dihydrogen phosphate), monoester with choline hydroxide, inner salt, L-;MFCD00133434;1-Lauroyl-2-lysolecithin;LYSOPC 12;UNII-V4Z2U6E9RE;1-Lauroyllysophosphatidylcholine;CHEMBL566871;DTXSID50942749;1-dodecanoyllysophosphatidylcholine;C12-LYSOPHOSPHATIDYLCHOLINE;LMGP01050009;Lauroyl-L-alpha-Lysophosphatidylcholine;.alpha.-L-Lysophosphatidylcholine dodecyl;L-.alpha.-Lysophosphatidylcholine, lauroyl;E78450;Q27145041;(R)-3-(dodecanoyloxy)-2-hydroxypropyl 2-(trimethylammonio)ethyl phosphate;12:0 Lyso PC, 1-lauroyl-2-hydroxy-sn-glycero-3-phosphocholine, powder;3-(Dodecanoyloxy)-2-hydroxypropyl 2-(trimethylazaniumyl)ethyl phosphate;(2R)-3-(dodecanoyloxy)-2-hydroxypropyl 2-(trimethylazaniumyl)ethyl phosphate;(R)-3-(Dodecanoyloxy)-2-hydroxypropyl (2-(trimethylammonio)ethyl) phosphate;2-[[(2R)-3-dodecanoyloxy-2-hydroxy-propoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-ammonium;Dodecanoyl-sn-glycero-3-phosphocholine (isomer 1) (LPC(12:0) i1) dagger double dagger;3,5,9-TRIOXA-4-PHOSPHAHENEICOSAN-1-AMINIUM, 4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-, INNER SALT, 4-OXIDE, (7R)-;3,5,9-Trioxa-4-phosphaheneicosan-1-aminium, 4,7-dihydroxy-N,N,N-trimethyl-10-oxo-, inner salt, 4-oxide, (R)-

Suppliers and Price of 1-Dodecanoyl-sn-glycero-3-phosphocholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 17 raw suppliers

Chemical Property of 1-Dodecanoyl-sn-glycero-3-phosphocholine

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：114.93000
Density:g/cm³
LogP:4.08940
Storage Temp.:−20°C
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:20
Exact Mass:439.26988968
Heavy Atom Count:29
Complexity:460

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)O
Isomeric SMILES:CCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)O

Technology Process of 1-Dodecanoyl-sn-glycero-3-phosphocholine

There total 2 articles about 1-Dodecanoyl-sn-glycero-3-phosphocholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 112-16-3
n-dodecanoyl chloride

: 28319-77-9,563-24-6
L-glycero-3-phosphorylcholine

: 20559-18-6
LPC (12:0)

Guidance literature:: L-glycero-3-phosphorylcholine; With di(n-butyl)tin oxide; In isopropyl alcohol; for 1h; Heating;

n-dodecanoyl chloride; With TEA; In isopropyl alcohol; at 20 ℃; for 0.583333h; Further stages.;
DOI:10.1039/b604636c

Reference yield:

: L-α-1,2-dilauroyl-sn-glycero-3-phosphocholine

: 20559-18-6
L-λ-lauroyl lysolecithin

Guidance literature:: With water; phospholipase A₂;
DOI:10.1021/j100288a018

Reference yield:

: 20559-18-6
LPC (12:0)

: 1,10-decanedioic acid mono-2-iodo-4-<(trifluoromethyl)-3H-diazirin-3-yl>benzyl ester

: 1-O-dodecanoyl-2-O-<9-<<<2-iodo-4-<(trifluoromethyl)-3H-diazirin-3-yl>benzyl>oxy>carbonyl>nonanoyl>-sn-glycero-3-phosphocholine

Guidance literature:: With pyridine; dmap; dicyclohexyl-carbodiimide; Yield given. Multistep reaction; 1.) CCl₄, 2.) CHCl₃;
DOI:10.1021/ja00116a013