2-chloro-N-(2-methylphenyl)benzamide

Base Information

• Chemical Name: 2-chloro-N-(2-methylphenyl)benzamide
• CAS No.: 2447-91-8
• Molecular Formula: C14H12 Cl N O
• Molecular Weight: 245.708
• Hs Code.: 2924299090
• NSC Number: 6922
• DSSTox Substance ID: DTXSID00947365
• Wikidata: Q82925153
• Mol file: 2447-91-8.mol

Synonyms:2-chloro-N-(2-methylphenyl)benzamide;2447-91-8;NSC6922;2-CHLORO-O-BENZOTOLUIDIDE;DTXSID00947365;NSC-6922;MFCD00087868;STK412540;AKOS001604692;SR-01000414631;SR-01000414631-1;Z27793166;2-Chloro-N-(2-methylphenyl)benzene-1-carboximidic acid

Chemical Property of 2-chloro-N-(2-methylphenyl)benzamide

Chemical Property:

• Vapor Pressure: 0.00112mmHg at 25°C
• Boiling Point: 300.5°Cat760mmHg
• Flash Point: 135.5°C
• PSA: 29.10000
• Density: 1.25g/cm³
• LogP: 3.97370
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 245.0607417
• Heavy Atom Count: 17
• Complexity: 269

Purity/Quality:

99%min ^*data from raw suppliers

2-CHLORO-N-(2-METHYLPHENYL)BENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1NC(=O)C2=CC=CC=C2Cl

Technology Process of 2-chloro-N-(2-methylphenyl)benzamide

There total 2 articles about 2-chloro-N-(2-methylphenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

o-chlorobenzoyl chloride (609-65-4) + o-toluidine (95-53-4) → 2-chloro-N-(2-methylphenyl)benzamide (2447-91-8)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1039/c5md00552c

Reference yield:

→ 2-chloro-N-(2-methylphenyl)benzamide (2447-91-8)

Guidance literature:

2-Chlor-benzoesaeure-chlorid u. o-Toluidin;

Reference yield: 86.0%

2-chloro-N-(2-methylphenyl)benzamide (2447-91-8) + phenylacetylene (536-74-3) → 3-benzylidene-2-(o-tolyl)isoindol-1-one

Guidance literature:

With 1,10-Phenanthroline; copper(II) oxide; potassium carbonate; In acetonitrile; at 90 ℃; Inert atmosphere;

upstream raw materials:

o-chlorobenzoyl chloride

o-toluidine

Refernces