Basic Orange 14

Base Information

• Chemical Name: Basic Orange 14
• CAS No.: 10127-02-3
• Deprecated CAS: 50977-21-4,60994-28-7
• Molecular Formula: C17H19N3.xCl2Zn.ClH
• Molecular Weight: 739.91400
• Hs Code.: 32041300
• European Community (EC) Number: 233-353-6
• DSSTox Substance ID: DTXSID20906035
• Mol file: 10127-02-3.mol

Synonyms:10127-02-3;Basic Orange 14;Euchrysine 3RX;Acridine Orange hemi(zinc chloride) salt;EINECS 233-353-6;zinc;3-N,3-N,6-N,6-N-tetramethylacridine-3,6-diamine;dichloride;hydrochloride;C17H19N3.xCl2Zn.ClH;N,N,N',N'-Tetramethylacridine-3,6-diamine monohydrochloride, compound with zinc dichloride;Acridine orange, colorant biologique;MFCD00081043;C17-H19-N3.x-Cl2-Zn.Cl-H;Euchrysin GNY;BasicOrange14;Acridine-orange-hemizinc-salt;Acridine orange (hemizinc salt);DTXSID20906035;AKOS027250830;A0132;A01-0009;J-000352;3,6-Bis(dimethylamino)acridinium chloride hemi(zinc chloride salt);6-METHYL-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-SULFONYLCHLORIDE;N,N,N inverted exclamation marka,N inverted exclamation marka-Tetramethylacridine-3,6-diamine monohydrochloride compd. with zinc dichloride;Zinc chloride--N~3~,N~3~,N~6~,N~6~-tetramethylacridine-3,6-diamine--hydrogen chloride (1/2/1/1)

Chemical Property of Basic Orange 14

Chemical Property:

• Appearance/Colour: brown powder
• Melting Point: 165 °C
• Boiling Point: 468.6ºC at 760 mmHg
• PKA: pKa -3.3(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain);0.2(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain);10.1(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain)
• Flash Point: 237.2ºC
• PSA: 38.74000
• LogP: 10.02050
• Storage Temp.: Store at RT.
• Sensitive.: Hygroscopic
• Solubility.: H2O: soluble1mg/mL, clear, orange to very deep orange
• Water Solubility.: soluble
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 435.001423
• Heavy Atom Count: 24
• Complexity: 298

Purity/Quality:

Acridine orange biological stain ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R20/21/22:; R68:
• Hazard Codes: Xn,Xi
• Statements: 68-20/21/22-36/37/38
• Safety Statements: 45-36/37-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CN(C)C1=CC2=C(C=C1)C=C3C=CC(=CC3=N2)N(C)C.Cl.[Cl-].[Cl-].[Zn+2]
• Uses: Fluorescent stain for nucleic acids. An RNA polymerase inhibitorAcridine Orange acts as a lysosomal dye. It is used for cell-cycle studies. It plays an important role as a nucleic acid-selective fluorescent cationic dye, which is useful for cell cycle determination. Further, it serves as an inhibitor of RNA polymerase. Acridine Orange, a cell-permeable metachromatic fluorescent cationic dye that intercalates DNA and RNA, is used in fluorescence and epiflouresence microscopy. Acridine Orange dye has been used to analyze mitochondria and lysosomal content by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.