3-(6-amino-9H-purin-9-yl)-cyclopentanol

Base Information

• Chemical Name: 3-(6-amino-9H-purin-9-yl)-cyclopentanol
• CAS No.: 142130-73-2
• Molecular Formula: C₁₀H₁₃N₅O
• Molecular Weight: 219.246
• Mol file: 142130-73-2.mol

Synonyms:Cyclopentanol,3-(6-amino-9H-purin-9-yl)-, (1R-cis)-; MDL 201112

Chemical Property of 3-(6-amino-9H-purin-9-yl)-cyclopentanol

Chemical Property:

• Vapor Pressure: 4.49E-11mmHg at 25°C
• Boiling Point: 506.3°Cat760mmHg
• PKA: 14.85±0.40(Predicted)
• Flash Point: 260°C
• PSA: 89.85000
• Density: 1.72g/cm³
• LogP: 1.07560

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(6-amino-9H-purin-9-yl)-cyclopentanol

There total 13 articles about 3-(6-amino-9H-purin-9-yl)-cyclopentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

(+)-<(1'R,4'S)-4'-hydroxy-2'-cyclopenten-1'-yl>-9-H-adenine (142695-05-4) → MDL 201,112 (142130-73-2)

Guidance literature:

With hydrogen; platinum(IV) oxide; In methanol; for 3h; under 1810.02 Torr;

DOI:10.1080/07328319608002028

Reference yield: 76.0%

(1S,4R)-4-hydroxy-1-(6-amino-9H-purin-9-yl)cyclopent-2-ene (142062-06-4) → MDL 201,451 (142130-73-2)

Guidance literature:

With hydrogen; platinum(IV) oxide; In methanol; for 3h; under 1810.02 Torr;

DOI:10.1021/jm950906t

Reference yield: 72.0%

(1'S,3'S)-3'-acetoxy-1'-(9-adenyl)cyclopentane (149342-60-9) → MDL 201,449 (142130-73-2)

Guidance literature:

With methanol; ammonia; for 48h; Autoclave; Saturated solution;

DOI:10.1016/j.tetlet.2012.01.101

upstream raw materials:

(1S,4R)-4-hydroxy-1-(6-amino-9H-purin-9-yl)cyclopent-2-ene

(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

Acetic acid (1R,4R)-4-methanesulfonyloxy-cyclopent-2-enyl ester

Acetic acid (1R,4S)-4-(6-amino-purin-9-yl)-cyclopent-2-enyl ester