2-Amino-3-phenylpropanoic acid hydrochloride

Base Information

• Chemical Name: 2-Amino-3-phenylpropanoic acid hydrochloride
• CAS No.: 27172-85-6
• Molecular Formula: C9H11 N O2 . Cl H
• Molecular Weight: 201.653
• Hs Code.: 2922499990
• European Community (EC) Number: 248-285-2
• DSSTox Substance ID: DTXSID00514738
• Mol file: 27172-85-6.mol

Synonyms:2-Amino-3-phenylpropanoic acid hydrochloride;3-Phenyl-DL-alanine hydrochloride;27172-85-6;3-Phenyl-DL-alanine HCl;EINECS 248-285-2;2-Amino-3-phenylpropanoicacidhydrochloride;2-amino-3-phenylpropanoic acid;hydrochloride;SCHEMBL245923;DTXSID00514738;ZAIZDXVMSSDZFA-UHFFFAOYSA-N;dl-phenylalanine hydrochloride salt;AKOS015919498;Phenylalanine--hydrogen chloride (1/1);FT-0757001;A23540;C73515

Chemical Property of 2-Amino-3-phenylpropanoic acid hydrochloride

Chemical Property:

• Boiling Point: 307.5°Cat760mmHg
• Flash Point: 139.8°C
• PSA: 63.32000
• Density: g/cm³
• LogP: 2.14330
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 201.0556563
• Heavy Atom Count: 13
• Complexity: 153

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC(C(=O)O)N.Cl

Technology Process of 2-Amino-3-phenylpropanoic acid hydrochloride

There total 51 articles about 2-Amino-3-phenylpropanoic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester (51987-73-6) → L-phenylalanine hydrochloride (17585-69-2,27172-85-6,28069-46-7,74496-49-4,79541-99-4)

Guidance literature:

With hydrogenchloride; In methoxybenzene;

DOI:10.1016/j.tetlet.2003.12.154

Reference yield: 96.0%

N-benzoyl-L-phenylalanine (2566-22-5) → L-phenylalanine hydrochloride (17585-69-2,27172-85-6,28069-46-7,74496-49-4,79541-99-4)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; water; at 100 ℃;

DOI:10.1039/c3ra42906g

Reference yield: 91.0%

C34H28Cl3N3NiO3 → L-phenylalanine hydrochloride (17585-69-2,27172-85-6,28069-46-7,74496-49-4,79541-99-4)

Guidance literature:

With hydrogenchloride; In methanol; water; at 70 ℃; for 2h;

DOI:10.1002/anie.201507273

upstream raw materials:

(2S)-2-azido-3-phenylpropanoic acid

N-<(S)-2'-amino-3-phenylpropanoyl>bornane-2,10-sultam hydrochloride

methyl 2-amino-3-phenylpropanoate hydrochloride

(R)-3-hydroxy-4,4-dimethyl-1-phenylpyrrolidin-2-one

Downstream raw materials:

Nα-phthaloyl-L-phenylalanine

N-(1-adamantylmethyl)-L-phenylalanine

(-)-4-[4-{(2-hydroxy-1-benzyl)ethylaminomethyl}benzyloxy]-3,5-bis(hydroxymethyl)phenylacetylene

L-Phenylalaninol