(2S,3R)-2-azanyl-3-methyl-pentanedioic acid

Base Information

Chemical Name:(2S,3R)-2-azanyl-3-methyl-pentanedioic acid
CAS No.:6070-75-3
Molecular Formula:C6H11NO4
Molecular Weight:161.1558
Hs Code.:
European Community (EC) Number:687-030-3
ChEMBL ID:CHEMBL290744
Nikkaji Number:J604.336D
Wikidata:Q27462604
Mol file:6070-75-3.mol

Synonyms:(2S,3R)-2-azanyl-3-methyl-pentanedioic acid;(2S,3R)-3-METHYLGLUTAMIC ACID;(2S,3R)-2-amino-3-methylpentanedioic acid;6070-75-3;(3r)-3-Methyl-L-Glutamic Acid;( inverted exclamation markA)-threo-3-Methylglutamic acid;33511-69-2;Glutamic acid, 3-methyl-;NSC 295435;63088-04-0;(+/-)-threo-3-Methylglutamic acid;SCHEMBL75174;CHEMBL290744;()-threo-3-Methylglutamic acid;(??)-threo-3-Methylglutamic acid;AKOS030230605;DB03810;PD071346;HY-101227;CS-0021014;Q27462604

Suppliers and Price of (2S,3R)-2-azanyl-3-methyl-pentanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of (2S,3R)-2-azanyl-3-methyl-pentanedioic acid

Chemical Property:

Boiling Point:329.4°Cat760mmHg
Flash Point:153°C
PSA：100.62000
Density:1.329g/cm³
LogP:0.20940
XLogP3:-3.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:161.06880783
Heavy Atom Count:11
Complexity:168

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC(=O)O)C(C(=O)O)N
Isomeric SMILES:C[C@H](CC(=O)O)[C@@H](C(=O)O)N

Technology Process of (2S,3R)-2-azanyl-3-methyl-pentanedioic acid

There total 2 articles about (2S,3R)-2-azanyl-3-methyl-pentanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 129397-27-9
(2S,3R)-2-Dibenzylamino-3-methyl-pentanedioic acid

: 2445-97-8,6070-75-3,6208-94-2,33511-69-2,33511-70-5,63088-04-0,76318-75-7,97550-61-3,274255-87-7
(+/-)-threo-3-methylglutamate

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 50 ℃; for 0.5h;
DOI:10.1246/cl.1990.377

Reference yield:

: 129397-19-9
(2R,3S)-2-Dibenzylamino-3-methyl-pentanedioic acid di-tert-butyl ester

: 2445-97-8,6070-75-3,6208-94-2,33511-69-2,33511-70-5,63088-04-0,76318-75-7,97550-61-3,274255-87-7
(+/-)-threo-3-methylglutamate

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / TFA / CH₂Cl₂ / 33 h / Ambient temperature

2: 65 percent / H₂ / Pd/C / ethanol / 0.5 h / 50 °C

With hydrogen; trifluoroacetic acid; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1246/cl.1990.377