3,25-Dihydroxy-23,26-epoxy-9,10-secocholesta-5,7,10-trien-26-one

Base Information

Chemical Name:3,25-Dihydroxy-23,26-epoxy-9,10-secocholesta-5,7,10-trien-26-one
CAS No.:71302-34-6
Molecular Formula:C₂₇H₄₀O₄
Molecular Weight:428.612
Hs Code.:
DSSTox Substance ID:DTXSID40991600
Mol file:71302-34-6.mol

Synonyms:DTXSID40991600;3,25-Dihydroxy-23,26-epoxy-9,10-secocholesta-5,7,10-trien-26-one

Suppliers and Price of 3,25-Dihydroxy-23,26-epoxy-9,10-secocholesta-5,7,10-trien-26-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3,25-Dihydroxy-23,26-epoxy-9,10-secocholesta-5,7,10-trien-26-one

Chemical Property:

Vapor Pressure:3.59E-16mmHg at 25°C
Boiling Point:586°C at 760 mmHg
PKA:13.13±0.40(Predicted)
Flash Point:190.9°C
Density:1.13g/cm³
XLogP3:5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:428.29265975
Heavy Atom Count:31
Complexity:795

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CC1CC(C(=O)O1)(C)O)C2CCC3C2(CCCC3=CC=C4CC(CCC4=C)O)C
Isomeric SMILES:C[C@H](CC1CC(C(=O)O1)(C)O)[C@H]2CC[C@@H]3[C@@]2(CCCC3=CC=C4C[C@H](CCC4=C)O)C

Technology Process of 3,25-Dihydroxy-23,26-epoxy-9,10-secocholesta-5,7,10-trien-26-one

There total 16 articles about 3,25-Dihydroxy-23,26-epoxy-9,10-secocholesta-5,7,10-trien-26-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76719-33-0
Acetic acid (3S,8S,9S,10R,13R,14S,17R)-17-[2-(4-hydroxy-4-methyl-5-oxo-tetrahydro-furan-2-yl)-1-methyl-ethyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

: 71302-34-6,76741-54-3,77714-46-6,77714-47-7,77714-48-8,77714-49-9,79702-76-4,80185-43-9,131801-98-4
(23R)-calcidiol lactone

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NBS, 2.) collidine, 3.) p-toluenesulfonic acid / 1.) CCl₄, 2.) xylene, reflux

2: alakaline / H₂O

3: 1.) iradiation, benzene, EtOH, 0 deg C, 2.5 min, 2.) benzene, EtOH, reflux, 1 h,

With 2,3,5-trimethyl-pyridine; N-Bromosuccinimide; toluene-4-sulfonic acid; In water;
DOI:10.1248/cpb.28.2852

Reference yield:

: 81305-33-1,82033-28-1
(R)-5-{2-[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-propyl}-3-methyl-dihydro-furan-2-one

: 71302-34-6,76741-54-3,77714-46-6,77714-47-7,77714-48-8,77714-49-9,79702-76-4,80185-43-9,131801-98-4
(23R)-calcidiol lactone

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) LDA, 2.) MoOPH, / 1.) THF, -78 deg C,

3: 1.) NBS, 2.) collidine, 3.) p-toluenesulfonic acid / 1.) CCl₄, 2.) xylene, reflux

4: alakaline / H₂O

5: 1.) iradiation, benzene, EtOH, 0 deg C, 2.5 min, 2.) benzene, EtOH, reflux, 1 h,

With 2,3,5-trimethyl-pyridine; N-Bromosuccinimide; MoO₅*pyridine*HMPA; toluene-4-sulfonic acid; lithium diisopropyl amide; In water;
DOI:10.1248/cpb.28.2852

Reference yield:

: 76719-32-9,81369-40-6,82079-13-8
5-{2-[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-3-(tetrahydro-pyran-2-yloxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-propyl}-3-hydroxy-3-methyl-dihydro-furan-2-one

: 71302-34-6,76741-54-3,77714-46-6,77714-47-7,77714-48-8,77714-49-9,79702-76-4,80185-43-9,131801-98-4
(23R)-calcidiol lactone

Guidance literature:: Multi-step reaction with 4 steps

2: 1.) NBS, 2.) collidine, 3.) p-toluenesulfonic acid / 1.) CCl₄, 2.) xylene, reflux

3: alakaline / H₂O

4: 1.) iradiation, benzene, EtOH, 0 deg C, 2.5 min, 2.) benzene, EtOH, reflux, 1 h,

With 2,3,5-trimethyl-pyridine; N-Bromosuccinimide; toluene-4-sulfonic acid; In water;
DOI:10.1248/cpb.28.2852