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Technology Process of Cilobradine (hydrochloride)

Cilobradine (hydrochloride)

Base Information
  • Chemical Name:Cilobradine (hydrochloride)
  • CAS No.:186097-54-1
  • Molecular Formula:C28H38 N2 O5 . Cl H
  • Molecular Weight:519.07
  • Hs Code.:
  • DSSTox Substance ID:DTXSID10582024
  • Mol file:186097-54-1.mol
Cilobradine (hydrochloride)

Synonyms:1,3,4,5-tetrahydro-7,8-dimethoxy-3-((1-(2-(3,4-dimethoxyphenyl)ethyl)-3-piperidinyl)methyl)-2H-3-benzazepin-2-one hydrochloride;DK-AH 268;DK-AH 269;DK-AH-268;DK-AH-269

Suppliers and Price of Cilobradine (hydrochloride)
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Sigma-Aldrich
  • DK-AH 269 ≥98% (HPLC), solid
  • 25mg
  • $ 660.00
  • Sigma-Aldrich
  • DK-AH 269 ≥98% (HPLC), solid
  • 5mg
  • $ 175.00
  • DC Chemicals
  • Cilobradine >98%
  • 10 mg
  • $ 152.00
  • DC Chemicals
  • Cilobradine >98%
  • 50 mg
  • $ 680.00
  • Crysdot
  • Cilobradinehydrochloride 98+%
  • 50mg
  • $ 589.00
  • Crysdot
  • Cilobradinehydrochloride 98+%
  • 10mg
  • $ 132.00
  • Crysdot
  • Cilobradinehydrochloride 98+%
  • 5mg
  • $ 80.00
  • ChemScene
  • Cilobradinehydrochloride ≥98.0%
  • 1mg
  • $ 120.00
  • Cayman Chemical
  • DK-AH 269 ≥98%
  • 10mg
  • $ 240.00
  • Cayman Chemical
  • DK-AH 269 ≥98%
  • 1mg
  • $ 30.00
Total 5 raw suppliers
Chemical Property of Cilobradine (hydrochloride)
Chemical Property:
  • Vapor Pressure:1.96E-17mmHg at 25°C 
  • Boiling Point:655.7°C at 760 mmHg 
  • Flash Point:350.4°C 
  • PSA：60.47000 
  • LogP:4.28070 
  • Storage Temp.:2-8°C 
  • Solubility.:H2O: ~20 mg/mL 
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:6
  • Rotatable Bond Count:9
  • Exact Mass:518.2547500
  • Heavy Atom Count:36
  • Complexity:663
Purity/Quality:

98%,99%, *data from raw suppliers

DK-AH 269 ≥98% (HPLC), solid *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:COC1=C(C=C(C=C1)CCN2CCCC(C2)CN3CCC4=CC(=C(C=C4CC3=O)OC)OC)OC.Cl
  • Isomeric SMILES:COC1=C(C=C(C=C1)CCN2CCC[C@@H](C2)CN3CCC4=CC(=C(C=C4CC3=O)OC)OC)OC.Cl
  • Uses DK-AH 269 has been used as a hyperpolarization-activated and cyclic nucleotide-gated channel (HCN) antagonist to study its effects on the inhibition of Ih?in?HCN-deficient hair cells of mice. It has also been used as an HCN blocker to study its effects on action potential firing in the suprachiasmatic nucleus (SCN) neurons.
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