3-Pyridinecarbonitrile, 4-(dimethylamino)-6-methyl-2-(4-morpholinyl)-

Base Information

Chemical Name:3-Pyridinecarbonitrile, 4-(dimethylamino)-6-methyl-2-(4-morpholinyl)-
CAS No.:137440-95-0
Molecular Formula:C13H18N4O
Molecular Weight:246.3082
Hs Code.:
DSSTox Substance ID:DTXSID90160187
Nikkaji Number:J426.520C
Wikidata:Q83028551
ChEMBL ID:CHEMBL1462908
Mol file:137440-95-0.mol

Synonyms:BRN 5439306;3-Pyridinecarbonitrile, 4-(dimethylamino)-6-methyl-2-(4-morpholinyl)-;137440-95-0;4-(Dimethylamino)-6-methyl-2-(4-morpholinyl)-3-pyridinecarbonitrile;MLS000036164;CHEMBL1462908;DTXSID90160187;HMS2283E03;STK543051;AKOS005472627;SMR000041628;SR-01000496142;SR-01000496142-1;4-(dimethylamino)-6-methyl-2-(morpholin-4-yl)pyridine-3-carbonitrile

Suppliers and Price of 3-Pyridinecarbonitrile, 4-(dimethylamino)-6-methyl-2-(4-morpholinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 3-Pyridinecarbonitrile, 4-(dimethylamino)-6-methyl-2-(4-morpholinyl)-

Chemical Property:

Vapor Pressure:4.89E-09mmHg at 25°C
Boiling Point:470.8°C at 760 mmHg
Flash Point:238.6°C
Density:1.18g/cm³
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:246.14806121
Heavy Atom Count:18
Complexity:318

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=N1)N2CCOCC2)C#N)N(C)C

Technology Process of 3-Pyridinecarbonitrile, 4-(dimethylamino)-6-methyl-2-(4-morpholinyl)-

There total 3 articles about 3-Pyridinecarbonitrile, 4-(dimethylamino)-6-methyl-2-(4-morpholinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.6%

: 110-91-8,99108-56-2
morpholine

: 137440-91-6
2-chloro-3-cyano-4-dimethylamino-6-methylpyridine

: 137440-95-0
4-Dimethylamino-6-methyl-2-morpholin-4-yl-nicotinonitrile

Guidance literature:: for 4h; Heating;
DOI:10.1007/BF00777684

Reference yield:

: 98694-78-1
4-(dimethylamino)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

: 137440-95-0
4-Dimethylamino-6-methyl-2-morpholin-4-yl-nicotinonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 89.6 percent / POCl₃, DMF / toluene / 6 h / Heating

2: 83.6 percent / 4 h / Heating

With N,N-dimethyl-formamide; trichlorophosphate; In toluene;
DOI:10.1007/BF00777684

Reference yield:

: 120650-90-0
α-cyano-β-dimethylaminocrotonamide

: 137440-95-0
4-Dimethylamino-6-methyl-2-morpholin-4-yl-nicotinonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 19.1 percent / dimethylformamide / 2 h / Heating

2: 89.6 percent / POCl₃, DMF / toluene / 6 h / Heating

3: 83.6 percent / 4 h / Heating

With N,N-dimethyl-formamide; trichlorophosphate; In N,N-dimethyl-formamide; toluene;
DOI:10.1007/BF00777684