(6S)-7-methylidene-8-oxo-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydronaphtho[2,3-d][1,3]dioxole-6-carboxylic acid

Base Information

Chemical Name:(6S)-7-methylidene-8-oxo-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydronaphtho[2,3-d][1,3]dioxole-6-carboxylic acid
CAS No.:120090-82-6
Molecular Formula:C22H20 O8
Molecular Weight:412.3894
Hs Code.:

Synonyms:Naphtho[2,3-d]-1,3-dioxole-6-carboxylicacid, 5,6,7,8-tetrahydro-7-methylene-8-oxo-5-(3,4,5-trimethoxyphenyl)-,(5R-trans)-; Thuriferic acid

Suppliers and Price of (6S)-7-methylidene-8-oxo-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydronaphtho[2,3-d][1,3]dioxole-6-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (6S)-7-methylidene-8-oxo-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydronaphtho[2,3-d][1,3]dioxole-6-carboxylic acid

Chemical Property:

Vapor Pressure:6.98E-14mmHg at 25°C
Boiling Point:571.1°Cat760mmHg
Flash Point:199.1°C
Density:1.41g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (6S)-7-methylidene-8-oxo-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydronaphtho[2,3-d][1,3]dioxole-6-carboxylic acid

There total 6 articles about (6S)-7-methylidene-8-oxo-5-(3,4,5-trimethoxyphenyl)-5,6,7,8-tetrahydronaphtho[2,3-d][1,3]dioxole-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 477-48-5,477-49-6,55515-07-6,60660-51-7,64550-42-1,64937-82-2,86594-36-7,130322-38-2
podophyllotoxone

: 120090-82-6
thuriferic acid

Guidance literature:: With potassium hydroxide; In methanol; for 0.5h; Ambient temperature;
DOI:10.1016/0040-4020(95)00275-D

Reference yield:

: 477-48-5
(5aR,8aS,9R)-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxole-5,8-dione

: 120090-82-6
thuriferic acid

Guidance literature:: With potassium tert-butylate; water; In tert-butyl alcohol; for 0.166667h; Yield given; Ambient temperature;
DOI:10.1016/S0040-4020(01)86096-8

Reference yield:

: 518-28-5
podofilox

: 120090-82-6
thuriferic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / PDC / CH₂Cl₂ / 3 h / 20 °C

2: 670 mg / KOH / methanol / 0.5 h / 20 °C

With potassium hydroxide; dipyridinium dichromate; In methanol; dichloromethane;
DOI:10.1016/j.tet.2005.11.068