4-Hydroxy-2-oxooxolan-3-yl [2-(4-methylphenyl)hydrazinyl](oxo)acetate

Base Information

Chemical Name:4-Hydroxy-2-oxooxolan-3-yl [2-(4-methylphenyl)hydrazinyl](oxo)acetate
CAS No.:7152-74-1
Molecular Formula:C13H14N2O6
Molecular Weight:294.264
Hs Code.:
NSC Number:24187
DSSTox Substance ID:DTXSID30992005

Synonyms:7152-74-1;NSC24187;DTXSID30992005;NSC-24187;4-Hydroxy-2-oxooxolan-3-yl [2-(4-methylphenyl)hydrazinyl](oxo)acetate

Suppliers and Price of 4-Hydroxy-2-oxooxolan-3-yl [2-(4-methylphenyl)hydrazinyl](oxo)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-Hydroxy-2-oxooxolan-3-yl [2-(4-methylphenyl)hydrazinyl](oxo)acetate

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.44g/cm³
XLogP3:1.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:294.08518617
Heavy Atom Count:21
Complexity:419

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)NNC(=O)C(=O)OC2C(COC2=O)O
Isomeric SMILES:CC1=CC=C(C=C1)NNC(=O)C(=O)O[C@@H]2[C@H](COC2=O)O

Technology Process of 4-Hydroxy-2-oxooxolan-3-yl [2-(4-methylphenyl)hydrazinyl](oxo)acetate

There total 6 articles about 4-Hydroxy-2-oxooxolan-3-yl [2-(4-methylphenyl)hydrazinyl](oxo)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 540-23-8
p-toluidine hydrochloride

: 50-81-7,98966-42-8
ascorbic acid

: 7152-74-1
(3R,4S)-4-hydroxy-2-oxotetrahydrofuran-3-yl 2-oxo-2-(2-(p-tolyl)hydrazinyl)acetate

Guidance literature:: p-toluidine hydrochloride; With hydrogenchloride; sodium nitrite; In water; at 10 ℃; for 0.0777778h; Flow reactor;

ascorbic acid; In water; at 20 ℃; for 0.433333h; under 3878.71 Torr; Flow reactor;
DOI:10.3390/molecules21070918

Reference yield: 55.0%

: p-toluenediazonium hydrogen sulfate

: 89-65-6,98966-42-8
isoascorbic acid

: 7152-74-1
(-)-(3R-cis)-mono(tetrahydro-4-hydroxy-2-oxo-3-furanyl)ester 2-(4-methyl-phenyl)hidrazide of ethanedioic acid

Guidance literature:: at 0 ℃;
DOI:10.1016/S0040-4039(00)93678-5

Reference yield:

: 106-49-0,12221-03-3
p-toluidine

: 89-65-6,98966-42-8
isoascorbic acid

: 7152-74-1
(-)-(3R-cis)-mono(tetrahydro-4-hydroxy-2-oxo-3-furanyl)ester 2-(4-methyl-phenyl)hidrazide of ethanedioic acid

Guidance literature:: With sulfuric acid; sodium nitrite; Yield given. Multistep reaction; 1) 2 - 5 deg C, 30 min; 2) water, 3 h, room temperature;
DOI:10.1021/ja00349a053